Sewing Hydrogels: Adhesion of Hydrogels Utilizing in Situ Polymerization of Linear Polymers inside Gel Networks
Sewing Hydrogels: Adhesion of Hydrogels Utilizing in Situ Polymerization of Linear Polymers inside Gel Networks
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DOI：
10.1021/acs.macromol.9b01084
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发表时间：
2019-07
期刊：
影响因子：
5.5
通讯作者：
Shingo Tamesue;T. Endo;Yuma Ueno;Fumiya Tsurumaki
中科院分区：
文献类型：
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作者：
Shingo Tamesue;T. Endo;Yuma Ueno;Fumiya Tsurumaki
水凝胶材料由于其作为人工组织（包括肌肉和软骨）的高潜力而备受关注。对于这些应用，水凝胶必须具有高的机械强度，并且用于将水凝胶粘附到活组织的粘合剂系统必须可用。近来，已经通过使用有机结构或无机化合物制备了具有高机械强度的各种水凝胶。然而，可应用于实际用途的水凝胶粘合剂系统的报道仍然很少。本文介绍了一种粘合剂水凝胶系统的制备，它可以使用和应用容易，使用在水凝胶网络中互穿的线性聚合物的原位聚合。此外，该方法允许产生氧化还原响应性粘合剂水凝胶系统。
Hydrogel materials attract much attention due to their high potential as artificial tissues including muscles and cartilages. For these applications, hydrogels must possess high mechanical strength, and adhesive systems for the adhesion of hydrogels to living tissues must be available. Recently, various hydrogels having high mechanical strength have been prepared by using organic structures or inorganic compounds. However, reports on adhesive systems for hydrogels that can be applied to practical use are still scarce. This paper describes the preparation of an adhesive hydrogel system, which can be used and applied easily, using in situ polymerization of linear polymers interpenetrated in the hydrogel networks. Additionally, this method allows to create a redox-responsive adhesive hydrogel system.