Secular trends and seasonality in first-time hospitalization for acute myocardial infarction - a Danish population-based study
Secular trends and seasonality in first-time hospitalization for acute myocardial infarction - a Danish population-based study
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DOI：
10.1016/j.ijcard.2003.10.026
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发表时间：
2004-12-01
影响因子：
3.5
通讯作者：
Sorensen, HT
中科院分区：
文献类型：
--
作者：
Fischer, T;Lundbye-Christensen, S;Sorensen, HT
背景：在过去的几十年里，急性心肌梗死的发病率在一些西方国家有所下降。急性心肌梗死的发病率和死亡率具有季节性。我们研究了急性心肌梗死发病率的变化是否与季节性变化有关。研究方法：该研究基于1983年1月1日至1999年12月31日在丹麦北日德兰郡出院登记处确定的17，989例首次急性心肌梗死住院患者。急性心肌梗死的季节性使用泊松回归模型进行估计。结果：发病率每年下降3.2%（95%可信区间：2.7-3.3%）。住院治疗遵循不同的季节模式，这取决于年龄，但不取决于性别。在< 59岁的人群中，季节模式以春季大高峰（4月/5月）和秋季小高峰为主。随着年龄的增长，春季高峰减少，秋季高峰增加，并移向12月。在>= 80岁的类别中，发现了一个由一个高峰（12月）和一个低谷（8月）主导的季节性模式。尽管急性心肌梗死住院率下降，但这些季节性模式的形状和程度在整个研究期间保持稳定。结论：1983年至1999年，首次急性心肌梗死的住院率有所下降，但季节性模式随时间推移保持稳定。(c)2004爱思唯尔爱尔兰有限公司保留所有权利。
Background: The incidence of acute myocardial infarction has declined in several Western countries during the last decades. The incidence and mortality of acute myocardial infarction follow a seasonal pattern. We examined if changes in the incidence of acute myocardial infarction were associated with any changes in seasonality. Methods: The study was based on 17,989 patients hospitalized with first-time acute myocardial infarction identified in the Hospital Discharge Registry of the County of North Jutland, Denmark, from I January 1983 to 31 December 1999. The seasonality of acute myocardial infarction was estimated using a Poisson regression model. Results: The incidence rate decreased by 3.2% (95% confidence interval: 2.7-3.3%) annually. Hospitalizations followed different seasonal patterns depending on age, but not on gender. In the < 59-year-old group, the seasonal pattern was dominated by a broad spring peak (April/May) and a minor autumn peak. With increasing age, the spring peak decreased while the autumn peak increased and moved towards December. A seasonal pattern dominated by one peak (December) and one trough (August) was found in the >= 80-year-old category. The shape and extent of these seasonal patterns remained stable throughout the study period despite the decline in hospitalizations for acute myocardial infarction. Conclusion: Hospitalizations for first-time acute myocardial infarction decreased from 1983 to 1999, but the seasonal pattern remained stable over time. (c) 2004 Elsevier Ireland Ltd. All rights reserved.