A qualitative assessment of barriers to antiretroviral therapy adherence among adolescents in western Kenya.
A qualitative assessment of barriers to antiretroviral therapy adherence among adolescents in western Kenya.
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DOI：
10.1080/15381501.2012.754392
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发表时间：
2014-10-01
期刊：
影响因子：
--
通讯作者：
Vreeman R
中科院分区：
文献类型：
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作者：
Kunapareddy CJ;Nyandiko W;Inui T;Ayaya S;Marrero DG;Vreeman R
抗逆转录病毒治疗（ART）需要几乎完全的坚持才能有效。本研究旨在确定肯尼亚西部接受抗逆转录病毒治疗的艾滋病毒感染青少年确定的促进药物依从性的关键因素。采用定性研究设计，在肯尼亚西部的一个城市和农村诊所进行了三个青少年焦点小组讨论。研究人群包括通过美国国际开发署- ampath艾滋病毒护理系统接受抗逆转录病毒治疗的感染艾滋病毒的青少年。一名训练有素的协调员使用半结构化访谈指南用斯瓦希里语组织小组，探讨服药经验的多个方面。使用持续比较、渐进式编码和三角测量来分析转录的焦点小组对话。这些青少年描述了一个关于艾滋病毒的负面社会观念的背景，需要保密的生活方式，并尽量减少分享有关艾滋病毒或抗逆转录病毒治疗的信息。评估和解决青少年对药物保密和披露的恐惧和行为可以更准确地监测依从性和制定干预策略。
Antiretroviral therapy (ART) requires nearly perfect adherence to be effective. This study aims to identify key factors identified by HIV-infected adolescents on ART as contributing to medication adherence in western Kenya. Using a qualitative study design, three adolescent focus groups discussions were conducted at an urban and rural clinic site in western Kenya. The study population included HIV-infected adolescents receiving ART through the USAID-AMPATH HIV care system. A trained facilitator conducted groups in Kiswahili using a semi-structured interview guide probing multiple aspects of experience of taking medicines. Transcribed focus group dialogues were analyzed using constant comparison, progressive coding, and triangulation. The adolescents described a context of negative societal beliefs about HIV, necessitating a lifestyle of secrecy and minimizing the information shared about HIV or ART. Assessing and addressing adolescents’ fears and behaviors regarding medication secrecy and disclosure may enable more accurate monitoring of adherence and development of intervention strategies.