Dynamic snapshot gradient-echo imaging of head and neck malignancies: time dependency and quality of contrast-to-noise ratio
Dynamic snapshot gradient-echo imaging of head and neck malignancies: time dependency and quality of contrast-to-noise ratio
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头颈部恶性肿瘤的动态快照梯度回波成像：时间依赖性和对比噪声比的质量
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发表时间：
1996
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通讯作者：
W. Steinbrich
中科院分区：
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作者：
C. Gückel;K. Schnabel;M. Deimling;W. Steinbrich
本研究的目的是评估对比增强MR成像中头颈部恶性肿瘤的对比噪声比（CNR）的时间依赖性。然后，我们将比较动态快照梯度回波（SGE）图像与常规自旋回波（SE）和快速自旋回波（FSE）序列的CNR。本文对15例鳞状细胞癌进行了T_1 W-SE、T_2 W-FSE、增强Gd-T_1 W-SE和T_1 W-SGE序列检查，后者进行了静态和动态增强。计算所有序列和邻近组织的CNR，并确定达到最大CNR的时间（Tmax）用于动态研究。CNR具有时间依赖性，在6-18和60-160 s有两个不同的Tmax，对应于两种不同的肿瘤增强模式。两种增强模式均与不同的组织学表现或肿瘤分级无关。Gd-TlW-SGE图像的CNR改善。与口底和舌根的T1 W-SE和Gd-TlW-SE图像相关的改善具有统计学显著性。动态Gd-TlW-SGE测量的良好CNR证明了该方法的进一步研究以改善肿瘤描绘。
The purpose of this study was to evaluate the time dependency of the contrast-to-noise ratio (CNR) of head and neck malignancies during contrast-enhanced MR imaging. Then we would compare the CNR of dynamic snapshot gradient-echo (SGE) images with conventional spin-echo (SE) and fast spin-echo (FSE) sequences. Fifteen patients with squamous cell carcinomas were examined with T1W-SE, T2W-FSE, contrast-enhanced Gd-TlW-SE, and T1W-SGE sequences, the latter statically and contrast-enhanced dynamically. The CNR for all sequences and adjacent tissues was computed and the time to reach maximal CNR (Tmax) was determined for dynamic studies. The CNR was time dependent with two distinct Tmax at 6–18 and 60–160 s which corresponded to two different tumor enhancement patterns. Neither enhancement pattern correlated with distinct histologic findings or tumor grading. The CNR improved for the Gd-TlW-SGE images. The improvement was statistically significant in relation to T1W-SE and Gd-TlW-SE images at the floor of the mouth and at the tongue base. The good CNR of the dynamic Gd-TlW-SGE measurements justifies further investigations of this method in order to improve tumor delineation.