Functional association of the amygdala and ventral prefrontal cortex during cognitive evaluation of facial expressions primed by masked angry faces: an event-related fMRI study
Functional association of the amygdala and ventral prefrontal cortex during cognitive evaluation of facial expressions primed by masked angry faces: an event-related fMRI study
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DOI：
10.1016/j.neuroimage.2003.09.021
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发表时间：
2004-01-01
期刊：
影响因子：
5.7
通讯作者：
Yonekura, Y
中科院分区：
文献类型：
--
作者：
Nomura, M;Ohira, H;Yonekura, Y
本研究探讨了面孔表情认知评价过程中杏仁核和右前额叶腹侧皮质的功能联系。创造了一种情况，其中刺激的情绪效价通过使用阈下情感启动而无意识地被操纵。12名健康志愿者被要求评估目标面部的面部表情（500毫秒的持续时间），如“愤怒”，“中性”，或“快乐”。所有目标面部都表现出相对较弱的愤怒。就在呈现目标面部之前，呈现了持续时间为35 ms的三种条件的启动，愤怒面部、中性面部和白色空白。在这个过程中，受试者不能有意识地识别素数。与阈下呈现中性面孔或空白刺激相比，阈下呈现愤怒启动时右侧杏仁核的活动更大。最重要的是，右侧杏仁核的激活程度与右侧腹侧PFC的激活程度呈负相关，只有愤怒启动。此外，杏仁核的激活与受试者在目标面孔中识别愤怒时的判断率呈正相关。这些结果进行了讨论的权利PFC和杏仁核之间的功能关联及其对认知加工的影响。(C)2003年爱思唯尔公司All rights reserved.
The present study examined the functional association of the amygdala and right ventral prefrontal cortex (PFC) during cognitive evaluation of facial expressions. A situation was created where emotional valence of the stimuli was unconsciously manipulated by using subliminal affective priming. Twelve healthy volunteers were asked to evaluate the facial expressions of a target face (500-ms duration) such as "anger", "neutral", or "happy". All target faces expressed relatively weak anger. Just before the presentation of the target face, a prime of three conditions of 35-ms duration, angry face, neutral face, and white blank was presented. The subjects could not consciously identify the primes in this procedure. Activity in the right amygdala was greater with subliminal presentation of the angry prime compared with subliminal presentation of a neutral face or white-blank stimuli. Most importantly, the degree of activation of the right amygdala was negatively correlated with that of the right ventral PFC only with the anger prime. Furthermore, activation of the amygdala was positively correlated with rate of judgment when the subjects recognized anger in the target faces. These results are discussed in terms of the functional association between the right PFC and the amygdala and its influence on cognitive processing. (C) 2003 Elsevier Inc. All rights reserved.