FRESH TISSUE HARVEST FOR RESEARCH FROM PROSTATECTOMY SPECIMENS
FRESH TISSUE HARVEST FOR RESEARCH FROM PROSTATECTOMY SPECIMENS
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DOI：
10.1002/pros.2990250507
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发表时间：
1994-11-01
期刊：
影响因子：
2.8
通讯作者：
LEBOVITZ, RM
中科院分区：
文献类型：
--
作者：
WHEELER, TM;LEBOVITZ, RM
由于分子生物学和遗传技术的发展，学术医学中心对用于基础研究的新鲜组织的需求急剧增加。由于许多生物大分子的极端不稳定性，组织必须在从取出时间起尽可能少的延迟下收获。这种快速行动的必要性，经常是在不太理想的情况下，沿着可用于诊断目的的组织的明显损失，对负责癌症准确分级和分期的病理学家提出了艰巨的挑战。描述了一种新的方法，用于采购新鲜和新鲜冷冻的前列腺组织，对随后的形态学分析具有可接受的限制。(C)1994 Wiley-Liss，Inc.
As a consequence of molecular biological and genetic techniques, the demand for fresh tissue for basic research has increased dramatically at academic medical centers. Because of the extreme lability of many biological macromolecules, tissue must be harvested with the least possible delay from the time of removal. This necessity for quick action, frequently under less than optimal circumstances, along with the obvious loss of tissue available for diagnostic purposes, presents a daunting challenge to the pathologist responsible for accurate grading and staging of the cancer. A novel approach is described for the procurement of fresh and freshly frozen prostatic tissue with acceptable limitations on subsequent morphological analysis. (C) 1994 Wiley-Liss, Inc.