EFFECT OF SWALLOWED BOLUS VISCOSITY AND BODY POSITION ON ESOPHAGEAL TRANSIT, CONTRACTION AND PERCEPTION OF TRANSIT
EFFECT OF SWALLOWED BOLUS VISCOSITY AND BODY POSITION ON ESOPHAGEAL TRANSIT, CONTRACTION AND PERCEPTION OF TRANSIT
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DOI：
10.1590/s0004-28032015000100007
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发表时间：
2015-03-01
影响因子：
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通讯作者：
DANTAS, Roberto Oliveira
中科院分区：
文献类型：
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作者：
DALMAZO, Juciléia;APRILE, Lilian Rose Otoboni;DANTAS, Roberto Oliveira
背景-食道对吞咽的药丸有不同的反应.推注粘度和体位可能影响食管收缩和传输。目的：探讨推注粘度和体位对食管收缩、传输和感知的影响。方法：对26名无症状志愿者（13名男性和13名女性，年龄18-60岁，平均年龄：33.6（12.2）岁）的食管收缩、传输和传输感知进行了评价。使用固态导管测量食管收缩（测压）和传输（阻抗），传感器位于距离下食管括约肌5、10、15和20 cm处。每名志愿者一式两份并以随机顺序吞咽5 mL pH 3.3的等渗饮料的低粘性（LV）液体丸剂和5 mL高粘性（HV）糊状丸剂，所述糊状丸剂用稀释在50 mL水中的7.5g即食食品增稠剂（pH：6.4）制备。结果：在坐位，MV推注的总推注通过时间长于LV推注。仰卧位的食管通过时间长于坐位。在两个位置，HV推注的推注头提前时间均长于LV推注。仰卧位食管收缩幅度高于坐位。HV推注的推注传输感知比LV推注更频繁，与位置无关。结论-吞咽时吞咽丸剂的粘度和体位对食管收缩、传输和传输感知有影响。
Background - The esophagus has a different response in relation to the characteristics of a swallowed bolus. Bolus viscosity and body position may affect esophageal contraction and transit. Objective - To investigate the effect of bolus viscosity and body position on esophageal contraction, transit and perception. Methods - Esophageal contraction, transit and perception of transit were evaluated in 26 asymptomatic volunteers, 13 men and 13 women aged 18-60 years, mean: 33.6 (12.2) years. Esophageal contraction (manometry) and transit (impedance) were measured with a solid state catheter with sensors located 5, 10, 15, and 20 cm from the lower esophageal sphincter. Each volunteer swallowed in duplicate and in random sequence a 5 mL low viscous (LV) liquid bolus of an isotonic drink with pH 3.3, and a 5 mL high viscous (HV) paste bolus, which was prepared with 7.5 g of instant food thickener diluted in 50 mL of water (pH: 6.4). Results - Total bolus transit time, in the sitting position, was longer with the MV bolus than with the LV bolus. Esophageal transit was longer in the supine position than in the sitting position. Bolus head advance time was longer with the HV bolus than with the LV bolus in both positions. Contraction esophageal amplitude was higher in the supine position than in the sitting position. The perception of bolus transit was more frequent with the HV bolus than with the LV bolus, without differences related to position. Conclusion - The viscosity of the swallowed bolus and body position during swallows has an influence on esophageal contractions, transit and perception of transit.