Distributed network organization underlying feeding behavior in the mollusk Lymnaea.
Distributed network organization underlying feeding behavior in the mollusk Lymnaea.
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Mollusk Lymnaea中的饲料行为的分布式网络组织。
DOI：
10.1186/2042-1001-2-4
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发表时间：
2012-04-17
期刊：
影响因子：
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通讯作者：
Benjamin PR
中科院分区：
文献类型：
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作者：
Benjamin PR
本文综述的工作目的是利用腹足软体动物Lymneea的摄食系统，将单个神经元的特性与网络组织和行为联系起来。这种动物的食物摄取包括一系列有节奏的咬人动作，这些动作是通过对嘴唇和食道施加化学食物刺激而启动的。我们研究了单个神经元如何参与各种网络功能，这些功能是产生摄食行为所需的，如节奏产生、启动(‘决策’)、调制、饥饿和饱腹感。这些数据支持这样一种观点，即摄食行为是由分布式网络组织产生的，单个神经元经常参与不止一种网络功能，与其他神经元共享角色。在Lymneea摄食系统中，分布式网络中的多任务处理在经济上是明智的，因为在脊椎动物神经系统中，只有大约100个神经元可以执行由数百万个神经元执行的各种复杂任务。拥有互补的和潜在的替代网络功能机制也将增加网络的稳健性，在这个网络中，电生理记录实验中经常会遇到不同的放电率和突触强度。
The aim of the work reviewed here is to relate the properties of individual neurons to network organization and behavior using the feeding system of the gastropod mollusk, Lymnaea. Food ingestion in this animal involves sequences of rhythmic biting movements that are initiated by the application of a chemical food stimulus to the lips and esophagus. We investigated how individual neurons contribute to various network functions that are required for the generation of feeding behavior such as rhythm generation, initiation ('decision making'), modulation and hunger and satiety. The data support the view that feeding behavior is generated by a distributed type of network organization with individual neurons often contributing to more than one network function, sharing roles with other neurons. Multitasking in a distributed type of network would be 'economically' sensible in the Lymnaea feeding system where only about 100 neurons are available to carry out a variety of complex tasks performed by millions of neurons in the vertebrate nervous system. Having complementary and potentially alternative mechanisms for network functions would also add robustness to what is a 'noisy' network where variable firing rates and synaptic strengths are commonly encountered in electrophysiological recording experiments.