Neural responses in a fast periodic visual stimulation paradigm reveal domain-general visual discrimination deficits in developmental prosopagnosia.
Neural responses in a fast periodic visual stimulation paradigm reveal domain-general visual discrimination deficits in developmental prosopagnosia.
复制标题
快速周期性视觉刺激范式中的神经反应揭示了发育性面盲症中的一般视觉辨别缺陷。
DOI：
10.1016/j.cortex.2020.09.008
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发表时间：
2020
期刊：
影响因子：
--
通讯作者：
Fisher K
中科院分区：
文献类型：
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作者：
Fisher K
本研究采用快速周期性身份识别oddball刺激模式结合脑电图（EEG）研究了发展性面孔失认症（DP）患者视觉身份识别的选择性损害。在实验1中，神经反应不熟悉的面孔身份的变化强烈衰减与DP的个人相比，控制参与者，在相同的程度上直立和倒置的脸。在实验2中得到证实的面孔识别反应的减少，为DP中不熟悉的面孔识别的视觉处理缺陷提供了直接证据。重要的是，实验2表明，DP显示出衰减的神经反应，不仅与面部图像，但也与非面部图像（汽车）的身份怪人。这一结果有力地表明，快速身份相关的视觉加工障碍DP不仅限于面对，但也影响熟悉的类的非面部刺激。DP中的视觉辨别缺陷似乎不是面部特异性的。为了解释这些发现，我们提出了一个新的帐户DP作为一个域一般赤字快速视觉歧视。
We investigated selective impairments of visual identity discrimination in developmental prosopagnosia (DP), using a fast periodic identity oddball stimulation paradigm with electroencephalography (EEG). In Experiment 1, neural responses to unfamiliar face identity changes were strongly attenuated for individuals with DP as compared to Control participants, to the same extent for upright and inverted faces. This reduction of face identity discrimination responses, which was confirmed in Experiment 2, provides direct evidence for deficits in the visual processing of unfamiliar facial identity in DP. Importantly, Experiment 2 demonstrated that DPs showed attenuated neural responses to identity oddballs not only with face images, but also with non-face images (cars). This result strongly suggests that rapid identity-related visual processing impairments in DP are not restricted to faces, but also affect familiar classes of non-face stimuli. Visual discrimination deficits in DP do not appear to be face-specific. To account for these findings, we propose a new account of DP as a domain-general deficit in rapid visual discrimination.