Spinal cord involvement and systemic lupus erythematosus: clinical and magnetic resonance findings in 5 patients.
Spinal cord involvement and systemic lupus erythematosus: clinical and magnetic resonance findings in 5 patients.
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脊髓受累和系统性红斑狼疮：5 名患者的临床和磁共振结果。
DOI：
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发表时间：
1994
影响因子：
3.7
通讯作者：
L. Mantia
中科院分区：
文献类型：
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作者：
A. Salmaggi;E. Lamperti;M. Eoli;E. Venegoni;M. Bruzzone;G. Riccio;L. Mantia
我们报告了5例临床脊髓受累的急性或亚急性期患者的临床、磁共振成像(MRI)和实验室检查结果，其中2例先有脊髓炎发作，1例伴发脊髓炎，2例继发系统性红斑狼疮(SLE)。在我们的患者中发现了显著的临床和MRI异质性，这表明在SLE脊髓受累的发病机制中可能存在多种因素。对于表现为脊髓受累且没有其他解释的女性，应牢记未来演变为SLE的可能性，并应通过广泛和重复的临床和实验室评估来评估。
We report the clinical, magnetic resonance imaging (MRI) and laboratory findings in 5 patients with clinical spinal cord involvement with an acute or subacute course; in two of the patients the myelitic episode preceded, in one it was concomitant to, and in two it followed the diagnosis of systemic lupus erythematosus (SLE). The marked clinical and MRI heterogeneity detected in our patients suggests that various factors may be implied in the pathogenesis of spinal cord involvement in SLE. The possibility of a future evolution to SLE should be kept in mind in women presenting spinal cord involvement with no other explanation, and should be assessed by means of extensive and repeated clinical and laboratory evaluations.