Infection-Related Acute Care Events among Patients with Glomerular Disease
Infection-Related Acute Care Events among Patients with Glomerular Disease
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DOI：
10.2215/cjn.05900420
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发表时间：
2020-12-07
影响因子：
9.8
通讯作者：
Mottl, Amy
中科院分区：
文献类型：
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作者：
Glenn, Dorey A.;Henderson, Candace D.;Mottl, Amy
背景和目标 感染导致肾小球疾病患者的发病率和死亡率。我们试图描述治愈肾小球肾病网络 (CureGN) 研究参与者中感染相关急性护理事件的发生率并确定其危险因素。设计、设置、参与者和测量 CureGN 是一项前瞻性、多中心、队列研究，研究对象为患有活检样本证实的微小病变、FSGS、膜性肾病或 IgA 肾病/血管炎的儿童和成人。使用多变量 Cox 比例风险回归确定首次感染相关急性护理事件（住院或急诊就诊）时间的危险因素。结果 1741 名参与者（43% 为女性，41% 为 2.5 g/dl，尿蛋白肌酐比值
Background and objectives Infections contribute to patient morbidity and mortality in glomerular disease. We sought to describe the incidence of, and identify risk factors for, infection-related acute care events among Cure Glomerulonephropathy Network (CureGN) study participants. Design, setting, participants, & measurements CureGNis a prospective, multicenter, cohort study of children and adults with biopsy sample-proven minimal change disease, FSGS, membranous nephropathy, or IgA nephropathy/vasculitis. Risk factors for time to first infection-related acute care events (hospitalization or emergency department visit) were identified using multivariable Cox proportional hazards regression. Results Of 1741 participants (43% female, 41% 2.5 g/dl and urinary protein-creatinine ratio