GONADOTROPHIN RELEASING HORMONE PROVOKES PROLACTIN RELEASE IN HYPERGONADOTROPHIC HYPOGONADAL WOMEN: A RESPONSE NOT ALTERED BY DEXAMETHASONE
GONADOTROPHIN RELEASING HORMONE PROVOKES PROLACTIN RELEASE IN HYPERGONADOTROPHIC HYPOGONADAL WOMEN: A RESPONSE NOT ALTERED BY DEXAMETHASONE
复制标题
促性腺激素释放激素刺激性腺激素分泌过多的女性释放催乳素：地塞米松不会改变这一反应
作者：
W. Georgitis;G. Treece;F. Hofeldt
本文研究了7例性腺功能亢进的性腺功能减退症患者和4例优生腺功能正常的女性对静脉注射100μg促性腺激素释放激素的催乳素反应。性腺功能低下组催乳素平均基础水平为7.3±1.6 ng/ml，峰值为20.8±5.2 ng/ml，与优性腺妇女平均基础水平7.7±1.2 ng/ml相比无明显变化。地塞米松抑制不改变促性腺激素或催乳素对GnRH的反应。
The prolactin response to 100 μg of intravenous gonadotrophin releasing hormone was studied in seven hypergonadotrophic hypogonadal and four eugonadal women. Prolactin rose from a mean basal level of 7·3 ± 1·6 ng/ml to a mean peak level of 20·8 ± 5·2 ng/ml in the hypogonadal women, and did not change significantly from a mean basal level of 7·7 ± 1·2 ng/ml in the eugonadal women. Dexamethasone suppression did not alter the gonadotrophin or prolactin response to GnRH.
黄体生成素释放因子激动剂诱导催乳素和黄体生成素同时脉冲式释放。
DOI：
10.1210/jcem-52-5-934
发表时间：
1981
期刊：
The Journal of clinical endocrinology and metabolism
影响因子：
--
作者：
Casper,RF;Yen,SS
通讯作者：
Yen,SS