A Common Atoms Model for the Bayesian Nonparametric Analysis of Nested Data.
A Common Atoms Model for the Bayesian Nonparametric Analysis of Nested Data.
复制标题
用于嵌套数据贝叶斯非参数分析的通用原子模型。
DOI:
10.1080/01621459.2021.1933499
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发表时间:
2023
影响因子:
3.7
通讯作者:
Mira,Antonietta
中科院分区:
文献类型:
--
作者:
Denti,Francesco;Camerlenghi,Federico;Guindani,Michele;Mira,Antonietta
The use of large datasets for targeted therapeutic interventions requires new ways to characterize the heterogeneity observed across subgroups of a specific population. In particular, models for partially exchangeable data are needed for inference on nested datasets, where the observations are assumed to be organized in different units and some sharing of information is required to learn distinctive features of the units. In this manuscript, we propose a nested common atoms model (CAM) that is particularly suited for the analysis of nested datasets where the distributions of the units are expected to differ only over a small fraction of the observations sampled from each unit. The proposed CAM allows a two-layered clustering at the distributional and observational level and is amenable to scalable posterior inference through the use of a computationally efficient nested slice sampler algorithm. We further discuss how to extend the proposed modeling framework to handle discrete measurements, and we conduct posterior inference on a real microbiome dataset from a diet swap study to investigate how the alterations in intestinal microbiota composition are associated with different eating habits. We further investigate the performance of our model in capturing true distributional structures in the population by means of a simulation study.
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影响因子:
1.9
作者:
D. Zuanetti;P. Müller;Yitan Zhu;Shengjie Yang;Yuan Ji
通讯作者:
Yuan Ji
DOI:
10.1111/rssb.12162
发表时间:
2017-01-01
影响因子:
5.8
作者:
Botev, Z. I.
通讯作者:
Botev, Z. I.
DOI:
--
发表时间:
2016
期刊:
影响因子:
--
作者:
Liang Hong;Ryan Martin
通讯作者:
Ryan Martin
DOI:
--
发表时间:
2006
期刊:
Conference on Uncertainty in Artificial Intelligence
影响因子:
--
作者:
I. Porteous;A. Ihler;Padhraic Smyth;M. Welling
通讯作者:
M. Welling
DOI:
10.1198/016214508000000553
发表时间:
2008-09-01
影响因子:
3.7
作者:
Rodriguez, Abel;Dunson, David B.;Gelfand, Alan E.
通讯作者:
Gelfand, Alan E.