A mitochondria-targeted fluorescent probe for imaging endogenous malondialdehyde in HeLa cells and onion tissues
A mitochondria-targeted fluorescent probe for imaging endogenous malondialdehyde in HeLa cells and onion tissues
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用于对 HeLa 细胞和洋葱组织中内源性丙二醛进行成像的线粒体靶向荧光探针
DOI：
10.1039/c7cc00512a
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发表时间：
2017-04-14
影响因子：
4.9
通讯作者：
Lin, Weiying
中科院分区：
文献类型：
--
作者：
He, Longwei;Yang, Xueling;Lin, Weiying
以苯并恶二唑为荧光探针，构建了一种检测丙二醛（MDA）的线粒体荧光探针（Mito-FMP）。Mito-FMP在水溶液体系中对MDA的响应具有很大的光信号增强（774倍），并且具有监测HeLa细胞和洋葱组织中内源性MDA的能力。
The mitochondria-targeted turn-on fluorescent probe (Mito-FMP) based on a benzoxadiazole platform was developed for detection of malondialdehyde (MDA). Mito-FMP performed with large enhancement of the optical signal (774-fold) in response to MDA in an aqueous system and has the capability of monitoring endogenous MDA in HeLa cells and onion tissues.