Effects of natural honey consumption in diabetic patients: an 8-week randomized clinical trial
Effects of natural honey consumption in diabetic patients: an 8-week randomized clinical trial
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DOI：
10.3109/09637480801990389
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发表时间：
2009-01-01
影响因子：
3.9
通讯作者：
Pajouhi, Mohammad
中科院分区：
文献类型：
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作者：
Bahrami, Mohsen;Ataie-Jafari, Asal;Pajouhi, Mohammad
目的观察天然蜂蜜对2型糖尿病患者体重及部分血液生化指标的影响。方法将48例2型糖尿病患者随机分为两组，蜂蜜组口服天然蜂蜜，对照组不服用蜂蜜。在研究开始前（0周）和8周后，测量体重并抽取空腹血。结果调整基线值后，两组空腹血糖无显著性差异。蜂蜜组体重、总胆固醇、低密度脂蛋白胆固醇、甘油三酯降低（P = 0.000），高密度脂蛋白胆固醇升高（P < 0.01）。该组血红蛋白A（1C）水平明显升高（P < 0.01）。结论本研究结果表明，食用蜂蜜8周可对糖尿病患者的体重和血脂产生有益影响。然而，由于观察到血红蛋白A（1C）水平增加，建议糖尿病患者谨慎食用这种食物。
Objectives We investigated the effect of natural honey on body weight and some blood biochemical indices of diabetic subjects.Methods Forty-eight diabetic type 2 patients were randomly assigned into two groups: the honey group received oral natural honey for 8 weeks, and the control group did not take honey. Before the onset of the study (week 0) and after 8 weeks, weight measurements were taken and fasting blood samples were drawn.Results After adjustment for the baseline values, there were no significant differences in the fasting blood sugars between the two groups. Body weight, total cholesterol, low-density lipoprotein-cholesterol and triglyceride decreased (P = 0.000), and high-density lipoprotein-cholesterol increased significantly (P < 0.01) in honey group. The levels of hemoglobin A(1C) increased significantly in this group (P < 0.01).Conclusion The results of this study demonstrate that 8-week consumption of honey can provide beneficial effects on body weight and blood lipids of diabetic patients. However, since an increase in the hemoglobin A(1C) levels was observed, cautious consumption of this food by diabetic patients is recommended.