A two-dimensional quadrupole ion trap mass spectrometer
A two-dimensional quadrupole ion trap mass spectrometer
复制标题
DOI：
10.1016/s1044-0305(02)00384-7
复制
发表时间：
2002-06-01
影响因子：
3.2
通讯作者：
Syka, JEP
中科院分区：
文献类型：
--
作者：
Schwartz, JC;Senko, MW;Syka, JEP
本文介绍了线性或二维(2-D)四极离子陷阱作为高性能质谱仪的应用。质量分析是通过使用质量选择不稳定操作模式将离子从其中一个棒中的狭缝中喷射出来来执行的。利用共振喷射和激发来增强质量分析，并允许分离和激活离子以增强MS的能力。与具有相似质量范围的三维(3D)离子陷阱相比，观察到了更高的捕获效率和更大的离子容量。与3-D陷阱相当的质量分辨率很容易实现，包括在较慢的扫描速率下的高分辨率，尽管陷阱结构需要足够的机械公差。文中还讨论和论证了二维离子陷阱相对于三维离子陷阱的其他优点。(J am Soc MS Spectrm 2002，13,659-669)(C)2002年美国质谱学学会。
The use of a linear or two-dimensional (2-D) quadrupole ion trap as a high performance mass spectrometer is demonstrated. Mass analysis is performed by ejecting ions out a slot in one of the rods using the mass selective instability mode of operation. Resonance ejection and excitation are utilized to enhance mass analysis and to allow isolation and activation of ions for MS' capability. Improved trapping efficiency and increased ion capacity are observed relative to a three-dimensional (3-D) ion trap with similar mass range. Mass resolution comparable to 3-D traps is readily achieved, including high resolution at slower scan rates, although adequate mechanical tolerance of the trap structure is a requirement. Additional advantages of 2-D over 3-D ion traps are also discussed and demonstrated. (J Am Soc Mass Spectrom 2002, 13, 659-669) (C) 2002 American Society for Mass Spectrometry.