Clinical diagnosis of cerebral amyloid angiopathy: Validation of the Boston Criteria

Clinical diagnosis of cerebral amyloid angiopathy: Validation of the Boston Criteria
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DOI:
10.1212/wnl.56.4.537
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发表时间:
2001-02-27
期刊:
影响因子:
9.9
通讯作者:
Greenberg, SM
Greenberg, SM
中科院分区:
医学1区
文献类型:
--
作者:
Knudsen, KA;Rosand, J;Greenberg, SM

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作者通过临床病理相关性来评估脑淀粉样血管病(CAA)波士顿诊断标准的有效性。在年龄大于或等于55岁的原发性大叶出血患者的前瞻性队列中,从39例可获得病理组织的患者中,有13例患者被临床诊断为可能的CAA。所有13例患者均经神经病理学证实为CAA。这个小的病理序列表明,可能的CAA诊断可以在生活中进行,准确度很高。
The authors performed clinical-pathologic correlation to assess the validity of the Boston diagnostic criteria for cerebral amyloid angiopathy (CAA). Thirteen subjects were diagnosed clinically with probable CAA from among 39 patients with available pathologic tissue in a prospective cohort of subjects aged greater than or equal to 55 years with primary lobar hemorrhage. All 13 individuals were confirmed neuropathologically as having CAA. This small pathologic series indicates that the diagnosis of probable CAA can be made during life with high accuracy.