Dietary Derived Sesquiterpenes from Phyllodesmium lizardensis

Dietary Derived Sesquiterpenes from Phyllodesmium lizardensis
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DOI:
10.1021/np800583e
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发表时间:
2009-02-01
影响因子:
5.1
通讯作者:
Koenig, Gabriele M.
Koenig, Gabriele M.
中科院分区:
生物学2区
文献类型:
--
作者:
Affeld, Sven;Kehraus, Stefan;Koenig, Gabriele M.

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研究了最近发现的新的风生纲物种Phyllodesmium lizardensis Burghardt,Schrodl和Wagele,2008年的次级代谢产物谱。到目前为止,P. lizardensis只在吕宋岛发现。对P. lizardensis的分析导致分离新的倍半萜(+)-3 β-羟基-α-muurolene(1)和(+)-3 β-乙酰氧基-α-muurolene(2)。对宿主珊瑚进行GC-MS分析,确定为异指珊瑚属,也显示存在化合物I和2,而同域的花粉直感属物种缺乏这些产物。这些结果表明,P. lizardensis特异性地螯合这些化合物从异爪螨属物种。
The recently discovered new aeolidean species Phyllodesmium lizardensis Burghardt, Schrodl and Wagele, 2008 was investigated concerning its secondary metabolite profile. P. lizardensis so far has only been found on Lizard Island. Analysis of P. lizardensis led to the isolation of the new sesquiterpenes (+)-3 beta-hydroxy-alpha-muurolene (1) and (+)-3 beta-acetoxy-alpha-muurolene (2). GC-MS analysis of the host coral, identified as Heteroxenia sp., also showed the presence of compounds I and 2, whereas a sympatric Xenia species lacks these products. These results indicate that P. lizardensis specifically sequesters these compounds from Heteroxenia sp.