Melanoma central nervous system metastases: current approaches, challenges, and opportunities.
Melanoma central nervous system metastases: current approaches, challenges, and opportunities.
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DOI：
10.1111/pcmr.12538
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发表时间：
2016-11
影响因子：
4.3
通讯作者：
Kluger HM
中科院分区：
文献类型：
--
作者：
Cohen JV;Tawbi H;Margolin KA;Amravadi R;Bosenberg M;Brastianos PK;Chiang VL;de Groot J;Glitza IC;Herlyn M;Holmen SL;Jilaveanu LB;Lassman A;Moschos S;Postow MA;Thomas R;Tsiouris JA;Wen P;White RM;Turnham T;Davies MA;Kluger HM
黑色素瘤中枢神经系统转移正在增加，这一患者群体面临的挑战仍然复杂。2015年12月，黑色素瘤研究基金会和Wistar研究所在宾夕法尼亚州费城举办了第一届黑色素瘤中枢神经系统（CNS）转移峰会。在这里，我们提供了一个审查的黑色素瘤脑转移研究领域的现状;确定关键的挑战和机遇，以改善黑色素瘤脑转移患者的结果;并设置一个框架，以优化未来的研究在这一关键领域。
Melanoma central nervous system metastases are increasing, and the challenges presented by this patient population remain complex. In December 2015, the Melanoma Research Foundation and the Wistar Institute hosted the First Summit on Melanoma Central Nervous System (CNS) Metastases in Philadelphia, Pennsylvania. Here, we provide a review of the current status of the field of melanoma brain metastasis research; identify key challenges and opportunities for improving the outcomes in patients with melanoma brain metastases; and set a framework to optimize future research in this critical area.