Postoperative complications in the Tube Versus Trabeculectomy (TVT) study during five years of follow-up.
Postoperative complications in the Tube Versus Trabeculectomy (TVT) study during five years of follow-up.
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DOI：
10.1016/j.ajo.2011.10.024
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发表时间：
2012-05
影响因子：
4.2
通讯作者：
Schiffman, Joyce C.
中科院分区：
文献类型：
--
作者：
Gedde, Steven J.;Herndon, Leon W.;Brandt, James D.;Budenz, Donald L.;Feuer, William J.;Schiffman, Joyce C.
描述小梁切除术(TVT)术后5年随访中遇到的并发症。多中心随机临床试验。17个临床中心。患者年龄18~85岁，既往接受小梁切除和/或白内障摘除人工晶状体植入术，眼压无控制的青光眼患者接受最大耐受性药物治疗，眼压≥18 mm Hg，≤40 mm Hg。导管分流术(350-mm2 Baerveldt青光眼植入物)或小梁切除术联合丝裂霉素C(丝裂霉素C 0.4 mg/mL，作用4min)。手术并发症、并发症的再次手术、视力和白内障进展。术后早期并发症：管组22例(21%)，小梁切除术组39例(37%)(P=0.012)。在5年的随访期内，小梁切除术组有38例(36%)发生了晚期并发症(P=0.81)，插管组有36例(34%)发生了术后晚期并发症。并发症再手术率管组为22%，小梁切除术组为18%(P=0.29)。小梁切除术组有晶状体眼9眼(43%)，管状体组有晶状体眼13眼(54%)。在TVT研究中观察到了大量的手术并发症，但大多数是一过性的和自限性的。小梁切除联合MMC术后早期并发症发生率高于管状分流术。术后晚期并发症、并发症的再次手术和白内障摘除的发生率在5年的随访中与两种手术方式相似。
To describe postoperative complications encountered in the Tube Versus Trabeculectomy (TVT) Study during 5 years of follow-up. Multicenter randomized clinical trial. Seventeen clinical centers. Patients 18 to 85 years of age who had previous trabeculectomy and/or cataract extraction with intraocular lens implantation and uncontrolled glaucoma with intraocular pressure (IOP) ≥18 mm Hg and ≤40 mm Hg on maximum tolerated medical therapy. Tube shunt (350-mm2 Baerveldt glaucoma implant) or trabeculectomy with mitomycin C (MMC 0.4 mg/mL for 4 minutes). Surgical complications, reoperations for complications, visual acuity, and cataract progression. Early postoperative complications occurred in 22 patients (21%) in the tube group and 39 patients (37%) in the trabeculectomy group (P = .012). Late postoperative complications developed in 36 patients (34%) in the tube group and 38 patients (36%) in the trabeculectomy group during 5 years of follow-up (P = .81). The rate of reoperation for complications was 22% in the tube group and 18% in the trabeculectomy group (P = .29). Cataract extraction was performed in 13 phakic eyes (54%) in the tube group and 9 phakic eyes (43%) in the trabeculectomy group (P = .43). A large number of surgical complications were observed in the TVT Study, but most were transient and self-limited. The incidence of early postoperative complications was higher following trabeculectomy with MMC than tube shunt surgery. The rates of late postoperative complications, reoperation for complications, and cataract extraction were similar with both surgical procedures after 5 years of follow-up.
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影响因子：
13.7
作者：
Samuelson, Thomas W.;Katz, L. Jay;Giamporcaro, Jane Ellen
通讯作者：
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影响因子：
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作者：
Lewis, Richard A.;von Wolff, Kurt;Samuelson, Thomas W.
通讯作者：
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影响因子：
4.2
作者：
Jampel, HD;Musch, DC;Guire, KE
通讯作者：
Guire, KE
影响因子：
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作者：
Gedde, SJ;Schiffman, JC;Brandt, JD
通讯作者：
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影响因子：
4.2
作者：
Gedde, Steven J.;Herndon, Leon W.;Schiffman, Joyce C.
通讯作者：
Schiffman, Joyce C.