Automated Recovery of the Center of Rotation in Optical Projection Tomography in the Presence of Scattering
Automated Recovery of the Center of Rotation in Optical Projection Tomography in the Presence of Scattering
复制标题
存在散射的光学投影断层扫描中旋转中心的自动恢复
DOI：
10.1109/titb.2012.2219588
复制
发表时间：
2013-01-01
影响因子：
7.7
通讯作者：
Ripoll, Jorge
中科院分区：
文献类型：
--
作者：
Dong, Di;Zhu, Shouping;Ripoll, Jorge
在光学投影层析成像中，旋转中心的确定是实现精确三维重建的关键步骤。不幸的是，目前的方法是不方便的，因为它们需要事先扫描的参考体模，高强度的小结构存在于标本中，或积极参与定心过程中。为了解决这些问题，本文提出了一种利用图形处理器并行编程的旋转中心快速自动搜索方法。我们的方法是基于一个两步搜索的方法，只利用那些部分的图像具有高的信噪比。我们已经测试了这种方法在非散射的离体样品和在体内标本的散射，如果蝇puereca相当大的贡献，在所有情况下恢复的旋转中心的精度1/4像素或更少。
Finding the center of rotation is an essential step for accurate 3-D reconstruction in optical projection tomography. Unfortunately, current methods are not convenient since they require either prior scanning of a reference phantom, small structures of high intensity existing in the specimen, or active participation during the centering procedure. To solve these problems this paper proposes a fast and automatic center of rotation search method making use of parallel programming in graphics processing units. Our method is based on a two step search approach making use only of those sections of the image with high signal-to-noise ratio. We have tested this method both in nonscattering ex vivo samples and in in vivo specimens with a considerable contribution of scattering such as Drosophila melanogaster pupae, recovering in all cases the center of rotation with a precision 1/4 pixel or less.