Antibodies to HTLV‐I in Nigerian blood‐donors, their relatives and patients with leukaemias, lymphomas and other diseases
Antibodies to HTLV‐I in Nigerian blood‐donors, their relatives and patients with leukaemias, lymphomas and other diseases
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尼日利亚献血者、其亲属以及白血病、淋巴瘤和其他疾病患者的 HTLV-I 抗体
DOI：
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发表时间：
1986
影响因子：
6.4
通讯作者：
G. Hunsmann
中科院分区：
文献类型：
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作者：
A. Fleming;R. Maharajah;M. Abraham;A. G. Kulkarni;S. Bhusnurmath;R. Okpara;E. Williams;I. Akinsete;J. Schneider;H. Bayer;G. Hunsmann
在尼日利亚736名成人献血者中的15名（2.0%）、20名慢性淋巴细胞白血病患者中的4名（20.0%）、30名非霍奇金淋巴瘤患者中的3名（10.0%）、12名伯基特淋巴瘤患者中的1名和7名急性淋巴细胞白血病患者中的1名的血清中检测到HTLV‐I抗体。来自几内亚和北方尼日利亚树木繁茂的热带稀树草原的献血者的阳性频率（3.6%）高于来自尼日利亚南部雨林和红树林沼泽的献血者（拉各斯为1.8%，卡拉巴尔为0.7%）。3例血清阳性淋巴瘤患者中有2例的临床表现和病程与日本和加勒比成人T细胞白血病/淋巴瘤患者相似。
Antibodies to HTLV‐I have been detected in sera from 15 (2.0%) of 736 adult blood‐donors in Nigeria, in 4 (20.0%) of 20 patients with chronic lymphatic leukaemia, 3 (10.0%) of 30 with non‐Hodgkin's lymphoma, one of 12 with Burkitt's lymphoma and one of 7 with acute lymphoblastic leukaemia. The frequency of positivily was higher (3.6%) in the blood‐donors from the guinea and wooded savanna of northern Nigeria than in those from the rain‐forest and mangrove swamps of southern Nigeria (1.8% in Lagos and 0.7% in Calabar). Two of the 3 seropositive patients with lymphoma had clinical presentation and courses similar to those of Japanese and Caribbean patients with adult T‐cell leukaemia/lymphoma.