Alternative Synthesis of 2-(4-Benzoyl-Piperazin-1-Ylmethyl)-5, 6-Dimethoxy-3-Methyl-[1, 4]Benzoquinone

Alternative Synthesis of 2-(4-Benzoyl-Piperazin-1-Ylmethyl)-5, 6-Dimethoxy-3-Methyl-[1, 4]Benzoquinone
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DOI:
10.3184/174751911x13099411630089
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发表时间:
2011-07
影响因子:
1.4
通讯作者:
J. Wang;J. Yang;R. Zhou;Bo Yang;Yuanshuang Wu
J. Wang;J. Yang;R. Zhou;Bo Yang;Yuanshuang Wu
中科院分区:
化学4区
文献类型:
--
作者:
J. Wang;J. Yang;R. Zhou;Bo Yang;Yuanshuang Wu

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The title compound was prepared by a reaction sequence starting from 2, 3, 4, 5-tetramethoxytoluene via Blanc chloromethylation reaction, oxidation and alkylation. The described method provides a good yield of the heterocyclic-Coenzyme Q analogue and is suitable for the synthesis of other analogues.