DISTRIBUTION OF CARDIAC-OUTPUT IN OVINE PREGNANCY

DISTRIBUTION OF CARDIAC-OUTPUT IN OVINE PREGNANCY
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DOI:
10.1152/ajpheart.1977.232.3.h231
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发表时间:
1977-01-01
影响因子:
--
通讯作者:
ROSENFELD, CR
ROSENFELD, CR
中科院分区:
其他
文献类型:
--
作者:
ROSENFELD, CR

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使用放射性核素标记的微球测量了 6 只未怀孕和 24 只怀孕母羊在妊娠 38-141 天的心输出量和器官血流量。从非妊娠状态到足月心输出量增加,从73.7.+-。每公斤母体体重 4.6 毫升/分钟至 148 .+-。 2.4 毫升/分钟/公斤,心率从 88.5 .+- 起。 10.3 至 106.+-。观察到 4.6 次/分钟,而平均动脉血压没有变化。近期,流向子宫和乳腺的血液约占心输出量的 18%。流向非生殖器官的血流量从 76.6.+- 增加。非妊娠状态下每公斤非生殖组织 6.8 毫升/分钟至 132 .+-。妊娠 130-140 天时每公斤 3.5 毫升/分钟 (P < 0.01)。未检测到肾血流量的显着变化。
Cardiac output and organ blood flows were measured in 6 nonpregnant and 24 pregnant ewes from 38-141 days of gestation employing radionuclide-labeled microspheres. From the nonpregnant state to term increases in cardiac output, from 73.7 .+-. 4.6 ml/min per kg of maternal weight to 148 .+-. 2.4 ml/min per kg, and heart rate, from 88.5 .+-. 10.3 to 106 .+-. 4.6 beats/min, were noted, while mean arterial blood pressure was unchanged. Near term, the blood flows to the uterus and mammary gland represented approximately 18% of cardiac output. The blood flow to nonreproductive organs increased from 76.6 .+-. 6.8 ml/min per kg of nonreproductive tissue in the nonpregnant state to 132 .+-. 3.5 ml/min per kg at 130-140 days'' gestation (P < 0.01). No significant changes in renal blood flow were detected.