Testing different communication formats on responses to imagined risk of having versus missing the GSTM1 gene.

Testing different communication formats on responses to imagined risk of having versus missing the GSTM1 gene.
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DOI:
10.1080/10810730.2012.688245
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发表时间:
2013
影响因子:
4.4
通讯作者:
Docherty S
Docherty S
中科院分区:
医学3区
文献类型:
--
作者:
Shepperd JA;Lipkus IM;Sanderson SC;McBride CM;O'Neill SC;Docherty S

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Genetic markers of lung cancer susceptibility, such as the common variant of the glutathione S-transferase Mu 1 gene (GSTM1-null), confer small probabilities of disease risk. We explored the influence of different approaches to communicating the small variations in risk associated with this biomarker. College smokers (N = 128) imagined that they had the GSTM1 wild-type vs. the GSTM1 null-type variant. We presented lung cancer risk in six ways that varied the risk format (absolute risk vs. incremental risk) and the presentation style of the information (no graphics vs. graphic display of foreground only vs. graphic display of foreground + background). Presentation style had minor effects. However, absolute risk information increased negative emotions more than did incremental risk information. Perceptions of risk and negative emotions were most profoundly affected by the difference between having the GSTM1 wild-type vs. the GSTM1 null-type variant. We discuss implications for conveying small probabilities related to genetic risk.
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