Effect of two breathing exercises (Buteyko and pranayama) in asthma: a randomised controlled trial
Effect of two breathing exercises (Buteyko and pranayama) in asthma: a randomised controlled trial
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DOI：
10.1136/thorax.58.8.674
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发表时间：
2003-08-01
期刊：
影响因子：
10
通讯作者：
Tattersfield, A
中科院分区：
文献类型：
--
作者：
Cooper, S;Oborne, J;Tattersfield, A
背景：哮喘患者对呼吸练习感兴趣，但其作用尚不确定。在一项平行组研究中，比较了 Buteyko 呼吸技术、模仿调息法（一种瑜伽呼吸技术）的装置和虚拟调息装置对支气管反应性和症状的影响，为期 6 个月。方法：90 名服用吸入皮质类固醇的哮喘患者在为期 2 周的试验后被随机分配到 Eucapnic Buteyko 呼吸、使用 Pink City 肺锻炼器 (PCLE) 来模仿调息或 PCLE安慰剂装置。受试者每天在家练习两次这些技术，持续 6 个月，然后是可选的类固醇减少阶段。主要结果指标是症状评分和乙酰甲胆碱剂量变化，导致前 6 个月内 FEV1 (PD20) 下降 20%。 结果：69 名患者 (78%) 完成了研究。 3个月或6个月时，三组之间的PD20没有显着差异。 PCLE 组和安慰剂组的症状相对稳定，但 Buteyko 组的症状有所减轻。 6 个月时症状评分的中位变化在安慰剂组中为 0（四分位距 -1 至 1），在 PCLE 组中为 -1（-2 至 0.75），在 Buteyko 组中为 -3（-4 至 0）（组间差异 p=0.003）。 6 个月时，Buteyko 组的支气管扩张剂使用量减少了每天两次；其他两组没有变化（p=0.005）。两组之间的 FEV1、病情加重或减少吸入皮质类固醇的能力没有差异。结论：Buteyko 呼吸技术可以改善症状并减少支气管扩张剂的使用，但似乎不会改变哮喘患者的支气管反应性或肺功能。粉红之城肺锻炼器没有显示任何益处。
Background: Patients with asthma are interested in the use of breathing exercises but their role is uncertain. The effects of the Buteyko breathing technique, a device which mimics pranayama (a yoga breathing technique), and a dummy pranayama device on bronchial responsiveness and symptoms were compared over 6 months in a parallel group study.Methods: Ninety patients with asthma taking an inhaled corticosteroid were randomised after a 2 week run in period to Eucapnic Buteyko breathing, use of a Pink City Lung Exerciser (PCLE) to mimic pranayama, or a PCLE placebo device. Subjects practised the techniques at home twice daily for 6 months followed by an optional steroid reduction phase. Primary outcome measures were symptom scores and change in the dose of methacholine provoking a 20% fall in FEV1 (PD20) during the first 6 months.Results: Sixty nine patients (78%) completed the study. There was no significant difference in PD20 between the three groups at 3 or 6 months. Symptoms remained relatively stable in the PCLE and placebo groups but were reduced in the Buteyko group. Median change in symptom scores at 6 months was 0 (interquartile range -1 to 1) in the placebo group, -1 (-2 to 0.75) in the PCLE group, and -3 (-4 to 0) in the Buteyko group (p=0.003 for difference between groups). Bronchodilator use was reduced in the Buteyko group by two puffs/day at 6 months; there was no change in the other two groups (p=0.005). No difference was seen between the groups in FEV1, exacerbations, or ability to reduce inhaled corticosteroids.Conclusion: The Buteyko breathing technique can improve symptoms and reduce bronchodilator use but does not appear to change bronchial responsiveness or lung function in patients with asthma. No benefit was shown for the Pink City Lung Exerciser.