Dual-energy CT for characterization of the incidental adrenal mass: preliminary observations.
Dual-energy CT for characterization of the incidental adrenal mass: preliminary observations.
复制标题
用于表征偶然肾上腺肿块的双能 CT：初步观察。
DOI：
10.2214/ajr.11.6957
复制
发表时间：
2012
期刊：
影响因子：
--
通讯作者：
H. Alkadhi
中科院分区：
文献类型：
--
作者：
R. Gnannt;M. Fischer;R. Goetti;C. Karlo;S. Leschka;H. Alkadhi
目标
我们研究的目的是评估对比增强双能 CT 重建的虚拟非增强图像与标准非增强 CT 相比，区分偶发肾上腺肿块的准确性。
材料和方法
140 名患者（平均年龄，74±9 岁）接受了腹部平扫和增强 CT，后者采用双能量采集，用于重建虚拟平扫图像。两个盲法独立读取器（R1 和 R2）使用优化的双能三材料分解算法测量标准未增强和虚拟未增强图像上每个偶然肾上腺质量的衰减。
结果
135 名患者中有 42 名（31%）发现了 51 个偶然的肾上腺肿块； 39 例偶发肾上腺肿块≥1 cm。根据平扫 CT，51 个偶然发生的肾上腺肿块中的 29 个和 39 个≥1 cm 的偶然发生的肾上腺肿块中的 22 个被分类为良性（HU<10）。虚拟未增强图像质量被评为良好或有轻度损伤（R1 为 2.45±0.83，R2 为 2.45±0.99）。未增强图像中的图像噪声为 12.7±3.6 HU，虚拟未增强图像中的图像噪声为 8.8±2.0 HU (p<0.001)。对于所有偶发肾上腺肿块（5.9±21.0 HU vs 7.0±20.6 HU，p = 0.48）和≥1 cm 的那些（6.6±18.5 HU vs 7.9±18.3 HU，p = 0.87），未增强和虚拟未增强图像之间的偶发肾上腺肿块衰减没有显着差异。用于表征可能良性的偶然肾上腺肿块的虚拟未增强图像的敏感性、特异性和准确性对于 R1 分别为 76%、82% 和 78%，对于 R2 分别为 79%、95% 和 86%。对于偶发肾上腺肿块≥1 cm，R1 的敏感性、特异性和准确性增加至 95%、100% 和 97%，R2 增加至 91%、100% 和 95%。
结论
与标准非增强 CT 相比，从腹部对比增强双能 CT 重建虚拟非增强图像可以更准确地表征偶发肾上腺肿块，在偶然肾上腺肿块测量≥1 cm 时获得最有利的结果。
OBJECTIVE
The purpose of our study was to evaluate the accuracy of virtual unenhanced images reconstructed from contrast-enhanced dual-energy CT for the differentiation of incidental adrenal masses in comparison with standard unenhanced CT.
MATERIALS AND METHODS
One hundred-forty patients (mean age, 74±9 years) underwent unenhanced and contrast-enhanced CT of the abdomen, the latter acquired with dual-energy for reconstruction of virtual unenhanced images. Two blinded and independent readers (R1 and R2) measured attenuation of each incidental adrenal mass on standard unenhanced and virtual unenhanced images using an optimized dual-energy three-material decomposition algorithm.
RESULTS
Fifty-one incidental adrenal masses were found in 42 of 135 patients (31%); 39 incidental adrenal masses were ≥1 cm. On the basis of unenhanced CT, 29 of 51 incidental adrenal masses and 22 of 39 incidental adrenal masses≥1 cm were classified as benign (HU<10). Virtual unenhanced image quality was rated as good or with mild impairment (2.45±0.83 for R1, 2.45±0.99 for R2). Image noise was 12.7±3.6 HU in unenhanced images and 8.8±2.0 HU in virtual unenhanced images (p<0.001). There was no significant difference in incidental adrenal mass attenuation between unenhanced and virtual unenhanced images for all incidental adrenal masses (5.9±21.0 HU vs 7.0±20.6 HU, p=0.48) and for those≥1 cm (6.6±18.5 HU vs 7.9±18.3 HU, p=0.87). Sensitivity, specificity, and accuracy of virtual unenhanced images for the characterization of incidental adrenal masses as probably benign were 76%, 82%, and 78% for R1 and 79%, 95%, and 86% for R2, respectively. For incidental adrenal masses≥1 cm, sensitivity, specificity, and accuracy increased to 95%, 100%, and 97% for R1 and 91%, 100%, and 95% for R2.
CONCLUSION
Reconstruction of virtual unenhanced images from contrast-enhanced dual-energy CT of the abdomen allows the characterization of the incidental adrenal masses with a good accuracy compared with standard unenhanced CT, with the most favorable results in incidental adrenal masses measuring≥1 cm.
腹部的双能量和低KVP CT。
影响因子：
5
作者：
Yeh, Benjamin M.;Shepherd, John A.;Wang, Zhen J.;Teh, Hui Seong;Hartman, Robert P.;Prevrhal, Sven
通讯作者：
Prevrhal, Sven