Melanocyte colonization and pigmentation of breast carcinoma: pathological and clinical aspects.
Melanocyte colonization and pigmentation of breast carcinoma: pathological and clinical aspects.
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DOI：
10.1155/2012/427628
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发表时间：
2012
影响因子：
0.6
通讯作者：
Jensen V
中科院分区：
文献类型：
--
作者：
Mele M;Laurberg T;Engberg Damsgaard T;Funder J;Jensen V
Introduction. Melanocyte colonization of breast carcinoma by nonneoplastic melanocytes of epidermal origin is a rare and serious condition first described in 1977. We report on the exceptional clinical and pathological features of this migration phenomenon in a 74-year-old patient. Discussion. The pathogenesis by which melanocyte migration takes place is not known, but a breached basement membrane is considered essential. Conclusion. Histological examination and additional staining of skin are essential to differentiate breast cancer melanosis from malignant melanoma.
