High-Speed and Low-Noise Multichannel System for Broadband Coherent Raman Imaging
High-Speed and Low-Noise Multichannel System for Broadband Coherent Raman Imaging
复制标题
用于宽带相干拉曼成像的高速、低噪声多通道系统
DOI：
10.1109/newcas49341.2020.9159786
复制
发表时间：
2020
期刊：
影响因子：
--
通讯作者：
D. Polli
中科院分区：
文献类型：
--
作者：
A. Ragni;G. Sciortino;M. Sampietro;G. Ferrari;A. Cadena;F. Vernuccio;G. Cerullo;D. Polli
宽带相干拉曼光谱技术是一种非侵入性和非破坏性的光谱技术，在分子和生物化合物的分析中得到越来越广泛的应用。本文介绍了第一个用于高速宽带拉曼成像的32路模块化平台，该平台能够同时采集和处理32个波长的光谱，具有多通道伪差分锁定结构，以补偿光源产生的额外噪声。该系统基于专门为宽带拉曼应用而设计的定制集成CMOS前端，以及用于并行采集和实时数据处理的Xilinx Artix-7现场可编程门阵列。实验结果表明，该系统能够达到散粒噪声极限，获得像元驻留时间为100μ的拉曼图像。
Broadband coherent Raman is a non-invasive and non-destructive spectroscopic technique with growing applications in the analysis of molecules and biological compounds. This paper presents the first 32-ch modular platform for highspeed Broadband Raman Imaging, able to simultaneously acquire and process 32 wavelengths of the spectrum with a multichannel pseudo-differential lock-in structure for the compensation of the excess noise given by the laser source. The system is based on a custom integrated CMOS front-end, specifically designed for Broadband Raman applications, and a Xilinx Artix-7 FPGA for the parallel acquisition and real-time data elaboration. Experimental results show that the system is able to reach the shot noise limit and acquire a Raman image with a pixel dwell time of 100μs.