Neuropsychological and neurophysiological insights into hoarding disorder.

Neuropsychological and neurophysiological insights into hoarding disorder.
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DOI:
10.2147/ndt.s62084
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发表时间:
2015
影响因子:
3.2
通讯作者:
Baldwin PA
Baldwin PA
中科院分区:
医学4区
文献类型:
--
作者:
Grisham JR;Baldwin PA

文献摘要

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囤积症(HD)与严重的个人功能障碍有关,并构成严重的公共健康负担。囤积者在丢弃大量物品时会经历强烈的痛苦,这会导致极度混乱。研究和理论表明,囤积行为可能与信息处理的特定缺陷有关,特别是在注意力、记忆力和执行功能方面。人们对囤积行为的神经基础也越来越感兴趣。因此,本综述的主要目的是总结与囤积相关的神经心理学缺陷的现有证据,并回顾对其神经生理学基础的研究。我们还概述了囤积症的著名理论模型,并提供了基于经验的 HD 心理和医学治疗方法的最新描述。最后,我们讨论了未来阐明 HD 模型并改善这种致残性疾病的治疗机会和结果的重要途径。
Hoarding disorder (HD) is associated with significant personal impairment in function and constitutes a severe public health burden. Individuals who hoard experience intense distress in discarding a large number of objects, which results in extreme clutter. Research and theory suggest that hoarding may be associated with specific deficits in information processing, particularly in the areas of attention, memory, and executive functioning. There is also growing interest in the neural underpinnings of hoarding behavior. Thus, the primary aim of this review is to summarize the current state of evidence regarding neuropsychological deficits associated with hoarding and review research on its neurophysiological underpinnings. We also outline the prominent theoretical model of hoarding and provide an up-to-date description of empirically based psychological and medical treatment approaches for HD. Finally, we discuss important future avenues for elaborating our model of HD and improving treatment access and outcomes for this disabling disorder.