PRENATAL DIAGNOSIS OF EPIDERMOLYSIS BULLOSA LETALIS
PRENATAL DIAGNOSIS OF EPIDERMOLYSIS BULLOSA LETALIS
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大疱性表皮松解症的产前诊断
DOI：
10.1016/s0140-6736(80)91404-x
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发表时间：
1980
期刊：
影响因子：
--
通讯作者：
C. Gosden
中科院分区：
文献类型：
--
作者：
C. Rodeck;R. Eady;C. Gosden
大疱性表皮松解症的产前诊断是通过对妊娠 18 周胎儿镜直视下采集的胎儿皮肤活检标本进行电子显微镜检查来进行的。终止妊娠后确诊。羊水细胞的数量、大小和扫描电子显微镜外观均发现异常。这些技术对于许多其他情况的快速诊断研究具有巨大的潜力。
The prenatal diagnosis of epidermolysis bullosa letalis was made by electron microscopy of a biopsy specimen of fetal skin taken under direct vision by fetoscopy at 18 weeks' gestation. The diagnosis was confirmed after termination of pregnancy. Abnormalities were found in the number, size, and scanning-electron-microscope appearance of amniotic-fluid cells. These techniques have considerable potential for rapid diagnostic studies in a number of other conditions.