Reliability and validity of the TIMPSI for infants with spinal muscular atrophy type I.
Reliability and validity of the TIMPSI for infants with spinal muscular atrophy type I.
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DOI：
10.1097/pep.0b013e31828a205f
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发表时间：
2013
期刊：
影响因子：
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通讯作者：
Project Cure SMA Investigators Network
中科院分区：
文献类型：
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作者：
Krosschell KJ;Maczulski JA;Scott C;King W;Hartman JT;Case LE;Viazzo-Trussell D;Wood J;Roman CA;Hecker E;Meffert M;Léveillé M;Kienitz K;Swoboda KJ;Project Cure SMA Investigators Network
本研究检验了婴儿运动表现筛查项目测试（TIMPSI）在I型脊髓性肌萎缩症（SMA）婴儿中的信度和效度。训练后，12名评估者对4个I型SMA婴儿的视频进行评分，以评估评估者的信度。在一项SMA I型临床试验中，9名评估者对38名婴儿进行了两次测试，进一步评估了9名评估者的内测和重测信度。TIMPSI评分与到达能力和呼吸支持的关系也被检查。组内相关系数为0.97-0.98，组间视频评分信度良好。组内信度极好（组内相关系数0.91 ~ 0.98），重测信度r = 0.82 ~ r = 0.95。TIMPSI评分与到达能力相关（P≤0.05）。TIMPSI可以可靠地用于评估I型SMA婴儿的运动功能。此外，TIMPSI得分与接触能力有关，这是I型SMA儿童的一项重要功能技能。
This study examined the reliability and validity of the Test of Infant Motor Performance Screening Items (TIMPSI) in infants with type I spinal muscular atrophy (SMA). After training, 12 evaluators scored 4 videos of infants with type I SMA to assess interrater reliability. Intrarater and test-retest reliability was further assessed for 9 evaluators during a SMA type I clinical trial, with 9 evaluators testing a total of 38 infants twice. Relatedness of the TIMPSI score to ability to reach and ventilatory support was also examined. Excellent interrater video score reliability was noted (intraclass correlation coefficient, 0.97–0.98). Intrarater reliability was excellent (intraclass correlation coefficient, 0.91–0.98) and test-retest reliability ranged from r = 0.82 to r = 0.95. The TIMPSI score was related to the ability to reach (P ≤ .05). The TIMPSI can reliably be used to assess motor function in infants with type I SMA. In addition, the TIMPSI scores are related to the ability to reach, an important functional skill in children with type I SMA.