Winglets of the eye: dominant transmission of early adult pterygium of the conjunctiva.
Winglets of the eye: dominant transmission of early adult pterygium of the conjunctiva.
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DOI：
10.1136/jmg.27.6.392
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发表时间：
1990-06
影响因子：
4
通讯作者：
F. Hecht;Mark G Shoptaugh;M. G. S. Correspondence;Dr Hecht
中科院分区：
文献类型：
--
作者：
F. Hecht;Mark G Shoptaugh;M. G. S. Correspondence;Dr Hecht
翼状胬肉是一种翼状增厚的球结膜，它具有环境意义，因为它可能在长时间暴露在风和天气下时发生。我们描述了一个两代人患有翼状胬肉的家庭，没有异常暴露史。其中 6 名女性和 5 名男性（包括一组男性双胞胎），其中 7 例为双侧翼状胬肉，4 例为单侧翼状胬肉。这种疾病的发病时间是在成年早期，从十几岁到二十几岁。这种新的遗传形式可以通过发病年龄与先天性和中成人翼状胬肉区别开来，后者是作为常染色体显性遗传的。无论年龄，结膜翼状胬肉的治疗方法都是手术切除。
A pterygium, a wing-like thickening, of the bulbar conjunctiva is of environmental interest because it can occur on prolonged exposure to wind and weather. We describe a family with pterygium in two generations without a history of unusual exposure to the elements. There were six females and five males (including a set of male twins) with seven bilateral and four unilateral pterygia. The onset was unique in being in early adulthood, from the late teens through the twenties. This new genetic form can be distinguished by the age of onset from congenital and mid-adult pterygia, which are inherited as autosomal dominant traits. Irrespective of age, the treatment of conjunctival pterygium is surgical excision.