COMPARISON OF THE SPIKE PRECURSOR SEQUENCES OF CORONAVIRUS IBV STRAINS M41 AND 6/82 WITH THAT OF IBV BEAUDETTE

COMPARISON OF THE SPIKE PRECURSOR SEQUENCES OF CORONAVIRUS IBV STRAINS M41 AND 6/82 WITH THAT OF IBV BEAUDETTE
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DOI:
10.1099/0022-1317-67-12-2825
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发表时间:
1986-12-01
影响因子:
3.8
通讯作者:
BROWN, TDK
BROWN, TDK
中科院分区:
医学3区
文献类型:
--
作者:
BINNS, MM;BOURSNELL, MEG;BROWN, TDK

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本文测定了鸡传染性支气管炎病毒M_(41)株和6/82株纤突蛋白前体基因的核苷酸序列,并与已测定的Beaudette株进行了比较。发现两个马萨诸塞州菌株M41和Beaudette非常相似,只有3.7%的氨基酸不同。新分离株6/82与Beaudette的氨基酸序列差异较大,有13.8%的氨基酸序列与Beaudette的差异。确定的差异进行了讨论的穗蛋白的结构特征。
The nucleotide sequences of the spike precursor genes of infectious bronchitis virus strains M41 and 6/82 have been determined and compared with that of the Beaudette strain which we have previously sequenced. The two Massachusetts strains, M41 and Beaudette, were found to be remarkably similar, having only 3.7% of the amino acids different. The situation with 6/82, one of the new field isolates, is quite different and this strain had 13.8% of its amino acids different from Beaudette. The differences identified are discussed in terms of the structural features of the spike protein.