SYNTHESIS OF 3-HYDROXY-2-METHYLENE CARBONYL-COMPOUNDS - EFFECT OF CATALYST AND SUBSTRATE ON REACTION-RATE
SYNTHESIS OF 3-HYDROXY-2-METHYLENE CARBONYL-COMPOUNDS - EFFECT OF CATALYST AND SUBSTRATE ON REACTION-RATE
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DOI：
10.1080/00397918808081314
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发表时间：
1988-01-01
影响因子：
2.1
通讯作者：
ROOS, GHP
中科院分区：
文献类型：
--
作者：
DREWES, SE;FREESE, SD;ROOS, GHP
3-羟基奎宁环提高了标题化合物的形成速率，而乙酰化衍生物是一种不良催化剂。比较研究表明，在 Baylis-Hillman 反应中，甲基乙烯基酮比丙烯酸甲酯更具反应性。
3-Hydroxyquinuclidine enhances the rate of formation of the title compounds whereas the acetylated derivative is a poor catalyst. A comparative study shows that methyl vinyl ketone is more reactive than methyl acrylate in the Baylis-Hillman reaction.