Linear and Nonlinear Quantitative EEG Analysis
Linear and Nonlinear Quantitative EEG Analysis
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线性和非线性定量脑电图分析
DOI：
10.1109/memb.2008.923957
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发表时间：
2008
影响因子：
--
通讯作者：
Longlong Cheng
中科院分区：
文献类型：
--
作者：
B. Wan;Dong Ming;Hongzhi Qi;Zhaojun Xue;Yong Yin;Zhong;Longlong Cheng
提出了对中国汉族阿尔茨海默病（AD）患者脑电图的渐进研究。为此，天津大学神经工程实验室对中国汉族阿尔茨海默病患者进行了Q-EEG研究项目。该项目旨在帮助了解中国汉族群体中 AD 特有的脑电图变化与正常衰老的比较。为了这个目的，记录了包括这两类受试者在内的一大批招募的志愿者的静息脑电图。作为正常老年人，我们指的是与 AD 患者年龄匹配且不存在任何认知障碍或任何改变脑电图谱的潜在状况的人。我们目前的研究是通过三种不同的熵定义来检查 AD 中脑电图的背景活动：信息熵、互熵和近似熵 (ApEn)。该项目取得的进展有望为 AD 局部神经病理学提供富有成效的线索。
Presented is a progressive investigation on the EEG of Han Chinese patients with Alzheimer's disease (AD).Thus, an investigative project on Q-EEG was performed on the ethnic Han Chinese patients with AD by the Neural Engineering Lab of Tianjin University. This project was intended to contribute to the knowledge of EEG changes specific to AD in comparison with that to normal aging in the ethnic Han groups of China. With this aim, resting EEG was recorded from a large group of recruited volunteers including these two kinds of subjects. As normal elderly people, we mean people who could be age-matched with AD patients and who did not present any cognitive impairment or any potential condition altering the EEG profile. Our present studies were undertaken to examine the background activity of EEG in AD with three different entropy definitions: information entropy, mutual entropy, and approximate entropy (ApEn). The progress achieved in this project is expected to provide fruitful clues about local neuropathology of AD.