Salivary cortisol, heart rate, electrodermal activity and subjective stress responses to the Mannheim Multicomponent Stress Test (MMST)
Salivary cortisol, heart rate, electrodermal activity and subjective stress responses to the Mannheim Multicomponent Stress Test (MMST)
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DOI：
10.1016/j.psychres.2011.12.009
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发表时间：
2012-06-30
影响因子：
11.3
通讯作者：
Bohus, Martin
中科院分区：
文献类型：
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作者：
Reinhardt, Tatyana;Schmahl, Christian;Bohus, Martin
有效的心理应激诱导实验范式是实验应激研究的重要要求。可靠的协议是稀缺的，通常是费力和人力密集型。为了开发一种经济、易于应用的标准化应力方案，我们最近定制了曼海姆多组分应力试验（MMST）。这项测试已被证明会引起相对较高的压力反应，而不注重社会评价成分。在这项研究中，我们评估的变化，皮肤电活动和唾液皮质醇的MMST。MMST同时结合了认知（心算），情感（情感图片），声学（白色噪音）和动机压力（金钱损失）。本研究包括两个独立的实验。实验1招募80名女性受试者，实验2招募30名受试者（15名女性）。结果发现，MMST暴露后，大鼠皮肤电活动和唾液皮质醇水平均发生显著变化，主观应激反应和心率反应均显著增加。这些结果表明，MMST是一种经济的应激范式，也适用于研究应激反应的大型队列或多中心研究。由于社会评价威胁不是MMST的主要压力成分，因此该程序是其他既定压力协议的有用和补充替代方案。(C)2012爱思唯尔爱尔兰有限公司保留所有权利。
The availability of effective laboratory paradigms for inducing psychological stress is an important requirement for experimental stress research. Reliable protocols are scarce, usually laborious and manpower-intensive. In order to develop an economical, easily applicable standardized stress protocol, we have recently tailored the Mannheim Multicomponent Stress Test (MMST). This test has been shown to induce relatively high stress responses without focusing on social-evaluative components. In this study we evaluated changes in electrodermal activity and salivary cortisol in response to the MMST. The MMST simultaneously combines cognitive (mental arithmetic), emotional (affective pictures), acoustic (white noise) and motivational stressors (loss of money). This study comprised two independent experiments. For experiment 1,80 female subjects were recruited; 30 subjects (15 females) participated in experiment 2. Significant changes in electrodermal activity and salivary cortisol levels in response to MMST exposure were found. Subjective stress and heart rate responses were significantly increased in both experiments. These results indicate that the MMST is an economical stress paradigm which is also applicable in larger cohorts or multicenter studies for investigating stress reactions. As social-evaluative threat is not the main stress component of the MMST, this procedure represents a useful and complementary alternative to other established stress protocols. (C) 2012 Elsevier Ireland Ltd. All rights reserved.