Child and adolescent bipolar disorder: A review of the past 10 years

Child and adolescent bipolar disorder: A review of the past 10 years
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DOI:
10.1097/00004583-199709000-00008
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发表时间:
1997-09-01
影响因子:
13.3
通讯作者:
Luby, J
Luby, J
中科院分区:
医学1区
文献类型:
--
作者:
Geller, B;Luby, J

文献摘要

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目的:对过去 10 年儿童和青少年双相情感障碍 (BP) 的流行病学、现象学、自然病程、合并症、神经细胞学和治疗进行回顾。提供此审查是为了让申请人为美国精神病学和神经病学委员会的重新认证做好准备。方法:使用过去 10 年来自 Medline 和其他搜索的文献、早期相关文章、作者的经验以及正在进行的国家心理健康研究所资助的项目“儿科双相情感障碍的现象学和课程”。结果:特定年龄、发育(儿童、青少年和成人)DSM-IV 标准表现;合并症和鉴别诊断;并提供剧集和课程功能。其中包括特定年龄的童年狂妄、性欲亢进和妄想的例子。讨论了鉴别诊断(例如特定语言障碍、性虐待、品行障碍 [CD]、精神分裂症、药物滥用)、自杀和 BP-II。结论:现有数据强烈表明,青春期前发病的 BP 是一种非发作性、慢性、快速循环、混合性躁狂状态,可能与注意力缺陷多动障碍 (ADHD) 和 CD 共病,或者以 ADHD 和/或 CD 为首发表现。儿科血压的系统研究还处于起步阶段,需要持续和未来的研究来提供与发育相关的诊断方法和治疗。
Objective: To provide a review of the epidemiology, phenomenology, natural course, comorbidity, neuroblology, and treatment of child and adolescent bipolar disorder (BP) for the past 10 years. This review is provided to prepare applicants for recertification by the American Board of Psychiatry and Neurology. Method: Literature from Medline and other searches for the past 10 years, earlier relevant articles, and the authors' experience and ongoing National Institute of Mental Health-funded project ''Phenomenology and Course of Pediatric Bipolarity'' were used. Results: Age-specific, developmental (child, adolescent, and adult) DSM-IV criteria manifestations; comorbidity and differential diagnoses; and episode and course features are provided. Included are age-specific examples of childhood grandiosity, hypersexuality, and delusions. Differential diagnoses (e.g., specific language disorders, sexual abuse, conduct disorder [CD], schizophrenia, substance abuse), suicidality, and BP-II are discussed. Conclusion: Available data strongly suggest that prepubertal-onset BP is a nonepisodic, chronic, rapid-cycling, mixed manic state that may be comorbid with attention-deficit hyperactivity disorder (ADHD) and CD or have features of ADHD and/or CD as initial manifestations. Systematic research on pediatric BP is in its infancy and will require ongoing and future studies to provide developmentally relevant diagnostic methods and treatment.