Physical activity reduces the risk of subsequent depression for older adults
Physical activity reduces the risk of subsequent depression for older adults
复制标题
DOI：
10.1093/aje/kwf047
复制
发表时间：
2002-08-15
影响因子：
5
通讯作者：
Kaplan, GA
中科院分区：
文献类型：
--
作者：
Strawbridge, WJ;Deleger, S;Kaplan, GA
以前评估身体活动对抑郁症的保护作用的研究得出了相互矛盾的结果;最近的一项研究认为，排除残疾受试者会削弱任何观察到的效果。作者的目的是比较高水平的体力活动对有和没有排除残疾受试者的普遍和偶发抑郁症的影响。参与者是1994年阿拉米达县研究的1,947名社区居民，基线年龄为50-94岁，随访5年。使用精神障碍诊断和统计手册第四版（华盛顿，DC：美国精神病学协会，1994）中的标准测量抑郁症。体力活动用8分制量表测量;比值比基于量表上增加1分。即使调整了年龄、性别、种族、经济压力、慢性病、残疾、体重指数、饮酒、吸烟和社会关系，更多的体育活动对抑郁症和抑郁症都有保护作用。（校正比值比（OR）= 0.90，95%可信区间（CI）：0.79，1.01）和5年内发生抑郁症（校正OR = 0.83，95% CI：0.73，0.96）。排除残疾受试者不会减弱发生率结果（校正OR = 0.79，95% CI：0.67，0.92）。研究结果支持身体活动对老年人抑郁症的保护作用，并反对将残疾受试者排除在类似研究之外。
Previous studies assessing protective effects of physical activity on depression have had conflicting results; one recent study argued that excluding disabled subjects attenuated any observed effects. The authors' objective was to compare the effects of higher levels of physical activity on prevalent and incident depression with and without exclusion of disabled subjects, Participants were 1,947 community-dwelling adults from the Alameda County Study aged 50-94 years at baseline in 1994 with 5 years of follow-up. Depression was measured using criteria from the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (Washington, DC: American Psychiatric Association, 1994). Physical activity was measured with an eight-point scale; odds ratios are based upon a one-point increase on the scale. Even with adjustments for age, sex, ethnicity, financial strain, chronic conditions, disability, body mass index, alcohol consumption, smoking, and social relations, greater physical activity was protective for both prevalent depression (adjusted odds ratio (OR) = 0.90, 95% confidence interval (Cl): 0.79, 1.01) and incident depression (adjusted OR = 0.83, 95% Cl: 0.73, 0.96) over 5 years. Exclusion of disabled subjects did not attenuate the incidence results (adjusted OR = 0.79, 95% Cl: 0.67, 0.92). Findings support the protective effects of physical activity on depression for older adults and argue against excluding disabled subjects from similar studies.