Imino Glycals via Ruthenium-Catalyzed RCM and Isomerization
Imino Glycals via Ruthenium-Catalyzed RCM and Isomerization
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DOI：
10.1055/s-0033-1338615
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发表时间：
2014-03
期刊：
影响因子：
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通讯作者：
B. Schmidt;Sylvia Hauke;Nino Muehlenberg
中科院分区：
文献类型：
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作者：
B. Schmidt;Sylvia Hauke;Nino Muehlenberg
摘要N-烯丙基-N-高烯丙基胺通过季铵盐催化的辅助串联催化闭环复分解-异构化反应一步转化为环烯酰胺。该序列依赖于通过添加氢氧化物作为化学触发剂将复分解活性Ru-卡宾原位转化为异构化活性Ru-氢化物。
Abstract N-Allyl-N-homoallylamines were converted in one step into cyclic enamides via a ruthenium-catalyzed assisted tandem catalytic ring-closing metathesis–isomerization sequence. The sequence relies on the in situ transformation of a metathesis active Ru–carbene into an isomerization active Ru–hydride by addition of hydroxide as a chemical trigger.