Screening of Korean herbal medicines used to improve cognitive function for anti-cholinesterase activity
Screening of Korean herbal medicines used to improve cognitive function for anti-cholinesterase activity
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DOI：
10.1016/j.phymed.2004.03.001
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发表时间：
2004-09-01
期刊：
影响因子：
7.9
通讯作者：
Cho, JH
中科院分区：
文献类型：
--
作者：
Oh, MH;Houghton, PJ;Cho, JH
采用Ellman比色法对朝鲜传统医学中用于改善老年人记忆和认知的7种草药（菖蒲、石菖蒲、柴胡、番薯、朝鲜淫羊藿、茯苓和大枣）的甲氧磷提取物进行了胆碱酯酶抑制特性试验。在200 μ g/ml时，观察到A. calamus和E.朝鲜木。这些和其他草药测试的声誉的可能的基础进行了讨论，根据以前的调查，他们的化学和生物活性。(C)2004年Elsevier GmbH。All rights reserved.
Methanolic extracts of seven herbs (Acorus calamus, Acorus gramineus, Bupleurm facaltum, Dioscorea batatas, Epimedium koreanum, Poria cocos and Zizyphi jujuba) used in traditional Korean medicine for improvement of memory and cognition in old age were tested for cholinesterase inhibitory properties using the Ellman colorimetric method. Significant inhibition of the enzyme at 200 mug/ml was observed for extracts from A. calamus and E. koreanum. The possible bases for the reputation of these and the other herbs tested are discussed in the light of previous investigations into their chemistry and biological activity. (C) 2004 Elsevier GmbH. All rights reserved.