Long-term haematological improvement after non-intensive or no chemotherapy in juvenile myelomonocytic leukaemia and poor correlation with adult myelodysplasia spliceosome-related mutations.
Long-term haematological improvement after non-intensive or no chemotherapy in juvenile myelomonocytic leukaemia and poor correlation with adult myelodysplasia spliceosome-related mutations.
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幼年型粒单核细胞白血病非强化或无化疗后的长期血液学改善，与成人骨髓增生异常剪接体相关突变的相关性较差。
DOI：
10.1111/j.1365-2141.2012.09063.x
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发表时间：
2012
期刊：
影响因子：
--
通讯作者：
Sakashita K
中科院分区：
文献类型：
--
作者：
Matsuda K;Sakashita K
本文提供了有关儿童青少年粒单核细胞白血病（JMML）和化疗后观察到的血液学改善的信息。异基因造血干细胞移植（HSCT）是治疗JMML的唯一方法。它还提供了与尽管未接受化疗或在括号中注明的非强化化疗后仍显示长期血液学改善的患者数量相关的图表。
The article offers information on the children with juvenile myelomonocytic leukaemia (JMML) and the haematological improvement observed after the chemotherapy. It is suggested that allogeneic haematopoietic stem cell transplantation (HSCT) is only curative treatment for JMML. It also presents the chart related to the number of patients who showed long-term haematological improvement despite no chemotherapy or after non-intensive chemotherapy is indicated in parenthesis.