Liver Retransplantation How Much Is Too Much?
Liver Retransplantation How Much Is Too Much?
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DOI：
10.1016/j.cld.2016.12.013
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发表时间：
2017-05-01
影响因子：
5.1
通讯作者：
Hemming, Alan
中科院分区：
文献类型：
--
作者：
Berumen, Jennifer;Hemming, Alan
再次肝移植自肝移植开始以来就一直是一个具有挑战性的手术。随着时间的推移，结果有所改善，但再次移植的患者生存率仍然明显低于初次移植。许多研究都集中在预测结果的因素上。已经开发了模型来帮助预测风险，但再次移植的决定必须是多学科移植团队的决定。“什么时候太多”的问题？“可以由受体和供体因素指导，但这是一个必须由肝脏移植团队做出的道德决定。
Hepatic retransplantation has been surgically challenging since the beginning of liver transplant. Outcomes have improved over time, but patient survival with retransplant continues to be significantly worse than that of primary transplant. Many studies have focused on factors to predict outcomes. Models have been developed to help predict risk, but the decision for retransplant must be a multidisciplinary transplant team decision. The question of "when is too much?" can be guided by recipient and donor factors but is an ethical decision that must be made by the liver transplant team.