Static headspace-multicapillary column with gas chromatography coupled to ion mobility spectrometry as a simple approach for the discrimination of crude and processed traditional Chinese medicines
Static headspace-multicapillary column with gas chromatography coupled to ion mobility spectrometry as a simple approach for the discrimination of crude and processed traditional Chinese medicines
复制标题
静态顶空多毛细管柱气相色谱联用离子迁移谱作为鉴别中药生药和炮制品的简单方法
DOI：
10.1002/jssc.201400627
复制
发表时间：
2014-11-01
影响因子：
3.1
通讯作者：
Chen, Xiaocheng
中科院分区：
文献类型：
--
作者：
Cao, Gang;Shou, Qiyang;Chen, Xiaocheng
炮制过程可以改变中药的性质和化学变化，以适应不同的临床配药和制备要求。本研究建立了静态顶空-多毛细管柱气相色谱-离子迁移谱联用技术，用于中药饮片的快速、灵敏鉴别。以白芍为传统中药模型，通过将生品和炮制品分为两大类来说明这种方法的综合功效。白芍中主要成分的含量变化较大。该方法的建立为离子迁移谱法在中药内在质量控制及与其他炮制品或制剂的鉴别中的应用提供了依据。
The processing procedure can alter the nature and chemical transformation of traditional Chinese medicine to accommodate different clinical dispensing and preparation requirements. In this study, static headspace-multicapillary column with gas chromatography coupled to ion mobility spectrometry was developed for the rapid and sensitive discrimination of crude and processed traditional Chinese medicine. Using Radix Paeoniae Alba as a traditional Chinese medicine model, the combined power of this approach was illustrated by classifying the crude and processed Radix Paeoniae Alba samples into two main categories. The contents of the main components in Radix Paeoniae Alba varied significantly. The established method could promote the use of ion mobility spectrometry in intrinsic quality control and differentiation of herbal medicines from other processed products or preparations.