PREVALENCE OF BOWEL DYSFUNCTION IN PATIENTS WITH MULTIPLE-SCLEROSIS AND BLADDER DYSFUNCTION
PREVALENCE OF BOWEL DYSFUNCTION IN PATIENTS WITH MULTIPLE-SCLEROSIS AND BLADDER DYSFUNCTION
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DOI：
10.1007/bf00887825
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发表时间：
1995-01-01
影响因子：
6
通讯作者：
SWASH, M
中科院分区：
文献类型：
--
作者：
CHIA, YW;FOWLER, CJ;SWASH, M
排尿功能障碍在多发性硬化症(MS)病例中很常见。控制膀胱的神经通路与控制肛门直肠功能的神经通路非常接近，这可能会导致膀胱和肠道症状高度共存。对77名临床明确的多发性硬化症患者在神经内科门诊就诊，对他们的肠道功能进行了访谈。所有患者都有脊髓疾病的临床证据，并有不同程度的活动障碍和足够严重的膀胱控制障碍，需要寻求医疗咨询。这些患者中有36%患有便秘。尽管另有30%的人在3个多月前至少有过一次大便失禁，但20%的人有过“当前大小便失禁”的症状。部分患者既有便秘又有大便失禁。总共有52%的人目前至少有一种肠道症状。肠道症状的类型与排尿障碍的类型、MS的持续时间或残疾程度无关。肠道症状在MS患者中很常见，但即使在那些有排尿功能障碍的患者中也不是普遍存在的。虽然多发性硬化症患者的膀胱功能障碍明显与脊髓疾病有关，但肠功能障碍的神经学基础尚不清楚。
Urinary dysfunction is common in cases of multiple sclerosis (MS). The close proximity of those neural pathways which control the bladder to those which control anorectal function might be expected to lead to a high coexistence of bladder and bowel symptoms. Seventy-seven consecutive patients with clinically definite MS attending a uro-neurology clinic were interviewed about their bowel function. All patients had clinical evidence of spinal cord disease with varying degrees of impaired mobility and sufficiently severe disturbance of bladder control to seek medical advice. Thirty-six per cent of these patients had constipation. Twenty per cent had ''current incontinence'', although another 30% had had at least one episode of faecal incontinence more than 3 months previously. Some patients had both constipation and faecal incontinence. A total of 52% currently had at least one bowel symptom. The pattern of bowel symptoms did not correlate with the pattern of urinary disturbance, or the duration of MS, or the degree of disability. Bowel symptoms are common in patients with MS, but even in those with urinary dysfunction are not universal. Whereas bladder dysfunction in MS is clearly related to spinal cord disease, the neurological basis for the bowel dysfunction is less clear.