Neuropsychological investigations and event-related potentials in obstructive sleep apnea syndrome before and during CPAP-therapy
Neuropsychological investigations and event-related potentials in obstructive sleep apnea syndrome before and during CPAP-therapy
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DOI：
10.1016/s0022-510x(98)00131-2
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发表时间：
1998-07-15
影响因子：
4.4
通讯作者：
Malin, JP
中科院分区：
文献类型：
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作者：
Kotterba, S;Rasche, K;Malin, JP
阻塞性睡眠呼吸暂停综合征 (OSAS) 患者白天嗜睡，认知功能下降。该研究评估了 OSAS 中特殊认知障碍是否占主导地位。除了数字连接测试（ZVT）、判断信息处理和工作速度外，在开始经鼻持续气道正压通气（nCPAP）治疗之前，还对 31 名 OSAS 患者（50.1+/-9.4 岁）进行了计算机辅助（Wiener Testsystem 和 Zimmermann Testbatterie）神经心理学测试。对 10 名男性健康志愿者（48+/-9.9 岁）进行了相同的测试。此外，还记录了视觉诱发事件相关电位 (ERP)，并对 P3 分量进行了评估。警觉性受损（P
Patients with obstructive sleep apnea syndrome (OSAS) suffer from daytime sleepiness and a decline of cognitive functions. The study evaluated whether special cognitive disabilities predominate in OSAS. Besides the number connection test (ZVT), judging information processing and working velocity, computer-assisted (Wiener Testsystem and Zimmermann Testbatterie) neuropsychological testing was performed in 31 OSAS patients (50.1+/-9.4 years) before starting nasal continuous positive airway pressure (nCPAP) therapy. Identical test battery was performed in 10 male healthy volunteers (48+/-9.9 years). In addition visual evoked event-related potentials (ERPs) were recorded, the P3-component was evaluated. Impairment of alertness (P