Prostatic Urethral Lift: A New Minimally Invasive Treatment for Lower Urinary Tract Symptoms Secondary to Benign Prostatic Hyperplasia

Prostatic Urethral Lift: A New Minimally Invasive Treatment for Lower Urinary Tract Symptoms Secondary to Benign Prostatic Hyperplasia
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DOI:
10.1159/000441850
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发表时间:
2016-01-01
影响因子:
1.6
通讯作者:
Nuhoglu, Baris
Nuhoglu, Baris
中科院分区:
医学4区
文献类型:
--
作者:
Bozkurt, Aliseydi;Karabakan, Mehmet;Nuhoglu, Baris

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简介:前列腺尿道提升术(PUL)是一种用于治疗继发于良性前列腺增生(BPH)的下尿路症状(LUTSs)的微创手术。PUL手术包括植入物的放置,收回阻塞的前列腺叶。该程序在功能结果和生活质量(QoL)方面实现了可量化的改善,同时保留了勃起和射精功能。方法:回顾性分析2011年3月至2015年6月期间接受UroLift (R)手术诊断为BPH的17例患者。术前、术中及术后1年评价参数为人口学资料,术前、术中及术后1年评价结果为国际前列腺症状评分(IPSS)、尿流测量生活质量指数(QoL)、国际勃起功能指数(IIEF)及男性性健康射精功能问卷(MSHQ- ejd)。结果:从基线到干预后12个月的平均改善是显著的,总IPSS为9.6。Qmax提高了4.2个点,QoL提高了0.9个点,PVR降低了32%。术前、术后第3、12个月IIEF、MSHQ-EjD评分比较,差异无统计学意义(p < 0.05)。结论:PUL可快速改善尿潴留症状、生活质量和尿流量,并持续至干预后12个月。PUL是一种微创手术,在治疗继发于良性前列腺阻塞的麻烦的LUTS和保留全部性功能方面效果中等。(C) 2015 S. Karger AG,巴塞尔
Introduction: Prostatic urethral lift (PUL) is a minimally invasive procedure for the treatment of lower urinary tract symptoms (LUTSs) secondary to benign prostatic hyperplasia (BPH). The PUL procedure involves the placement of implants that retract the obstructing prostate lobes. This procedure achieves quantifiable improvements in functional outcomes and quality of life (QoL), while preserving erectile and ejaculatory functions. Methods: Seventeen patients diagnosed with BPH who had undergone the UroLift (R) procedure between March 2011 and June 2015 were retrospectively evaluated. The parameters evaluated in the pre-operative, intra-operative and 1-year post-operative period were demographic data, and pre-operative, intra-operative and 1-year post-operative results were obtained from the International Prostate Symptom Score (IPSS), Uroflowmetry QoL index, International Index of Erectile Function (IIEF) and Male Sexual Health Questionnaire (MSHQ) for ejaculatory function (MSHQ-EjD). Results: The average improvements from baseline to 12 months after intervention were significant for the total IPSS 9.6. There was a 4.2-point increase in Qmax, a 0.9-point improvement in QoL and a 32% decrease in PVR. No statistically significant difference was found in the IIEF and MSHQ-EjD scores when the pre-operative and post-operative 3rd and 12th month scores were evaluated (p > 0.05). Conclusions: PUL offers rapid improvement in voiding and storage symptoms, QoL and flow rate that is durable to 12 months after intervention. PUL is a minimally invasive procedure that has the moderate effect in treating troublesome LUTS secondary to benign prostatic obstruction and preserving total sexual function. (C) 2015 S. Karger AG, Basel