Meta-analysis of best-evidence synthesis?
Meta-analysis of best-evidence synthesis?
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DOI：
10.1111/j.1365-2753.1995.tb00005.x
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发表时间：
1995-09-01
影响因子：
2.4
通讯作者：
Eysenck, H J
中科院分区：
文献类型：
--
作者：
Eysenck, H J
这篇文章探讨了元分析的有用性，并阐明了许多对其工作的批评。试图概述在进行科学上有用和有意义的荟萃分析之前必须采取的预防措施。所遇到的问题包括样本、条件、干预措施和终点的异质性;焦点狭窄;回归曲线的线性;决定因素缺乏独立性;协同作用;相互矛盾的实验结果。有人建议，最佳证据合成，或理论导向的分析，可能是一个更安全的选择。
This article examines the usefulness of meta-analysis, and articulates many of the criticisms that have been made of its workings. An attempt is made to outline the precautions that have to be taken before a scientifically useful and meaningful meta-analysis can be carried out. The problems encountered include heterogeneity of samples, conditions, interventions and end-points; narrow focus; curvilinearity of regression; lack of independence of determinants; synergistic interactions; contradictory experimental results. It is suggested that best-evidence synthesis, or theory-directed analysis, might be a safer option.