Anatomical correlates of the functional organization in the human occipitotemporal cortex

Anatomical correlates of the functional organization in the human occipitotemporal cortex
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DOI:
10.1016/j.mri.2005.12.005
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发表时间:
2006-06-01
影响因子:
2.5
通讯作者:
Kim, Dae-Shik
Kim, Dae-Shik
中科院分区:
医学4区
文献类型:
--
作者:
Kim, Mina;Ducros, Mathieu;Kim, Dae-Shik

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由于目前死后解剖标记技术的局限性,人类大脑中功能不同区域之间的连通性是未知的。扩散张量成像(DTI)以前已被用来定义大的白色物质束的基础上,在活的人类大脑中众所周知的解剖标志。在本研究中,我们使用DTI结合功能磁共振成像(fMRI)来评估人类纹状体和功能定义的纹外腹侧皮质区之间的神经元连接。功能区确定与传统的功能磁共振成像映射程序,然后作为播种点在DTI分析,以确定皮质区之间的连接模式,从而产生的模式之间的连接人类枕腹侧视觉区在体内。(C)2006年爱思唯尔公司All rights reserved.
The connectivity between functionally distinct areas in the human brain is unknown because of the limitations posed by current postmortem anatomical labeling techniques. Diffusion tensor imaging (DTI) has previously been used to define large white matter tracts based on well-known anatomical landmarks in the living human brain. In the present study, we used DTI coupled with functional magnetic resonance imaging (fMRI) to assess neuronal connections between human striate and functionally defined extrastriate ventral cortical areas. Functional areas were identified with conventional fMRI mapping procedures and then used as seeding points in a DTI analysis to ascertain connectivity patterns between cortical areas, thus yielding the pattern of connections between human occipitoventral visual areas in vivo. (C) 2006 Elsevier Inc. All rights reserved.