Multiple inhalers confuse asthma patients

Multiple inhalers confuse asthma patients
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DOI:
10.1183/09031936.99.14510349
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发表时间:
1999-11-01
影响因子:
24.3
通讯作者:
Seydel, ER
Seydel, ER
中科院分区:
医学1区
文献类型:
--
作者:
van der Palen, J;Klein, JJ;Seydel, ER

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本研究调查了使用不同类型吸入器对成人哮喘患者吸入技术充分性的影响。测试了三个假设:首先,仅使用一种类型吸入器的患者比使用两种或多种类型吸入器的患者更常表现出适当的吸入技术;其次,使用干粉吸入器 (DPI) 组合的患者比使用定量吸入器 (MDI) 和 DPI 组合的患者更常表现出正确的吸入技术。第三,某些吸入器或吸入器组合比其他吸入器更容易出现错误的吸入技术。经常使用吸入类固醇治疗的成年哮喘门诊患者(n=321)参与了这项研究。所研究的吸入器一方面是 MDI,另一方面是 DPI Turbuhaler(R)、Diskhaler(R)、Cyclohaler(R)、Inhaler Ingelheim(R) 和 Rotahaler(R)。 在 208 名仅使用一种吸入器的成人哮喘患者中,71% 没有出现吸入错误,而 113 名使用两种或多种不同吸入器的患者中,这一比例为 61%。在采用 DPI 组合的患者中,68% 的患者正确执行了所有基本检查表项目,而采用“常规”MDI 和 DPI 组合的患者中,这一比例为 54%。仅使用 Diskhaler(R) 的患者犯的错误最少。只要有可能,应只开出一种类型的吸入器。如果组合不可避免,则 DPI 的组合优于 MDI 和 DPI。 Diskhaler 似乎是最安全的设备。
This study investigated the influence of the use of different types of inhalers on the adequacy of inhalation technique among adult asthmatics. Three hypotheses were tested: first, patients using only one type of inhaler will demonstrate adequate inhalation technique more often than those with two or more types, Secondly, patients using a combination of dry powder inhalers (DPIs) will demonstrate correct inhalation technique more often than those using the combination of a metered dose inhaler (MDI) and a DPI. Thirdly, some inhalers or combinations of inhalers are more prone to erroneous inhalation technique than others.Adult outpatients with asthma who regularly used inhaled steroid therapy (n=321) participated in the study. The inhalers investigated were MDIs on the one hand, and the DPIs Turbuhaler(R), Diskhaler(R), Cyclohaler(R), Inhaler Ingelheim(R) and Rotahaler(R) on the other.Of 208 adult asthmatics with only one inhaler, 71% made no inhalation errors versus 61% of 113 patients with two or more different inhalers. Of patients with a combination of DPIs 68% performed all essential checklist items correctly, versus 54% of patients,vith the combination of "regular" MDI and DPI. Patients using only the Diskhaler(R) made fewest errors.Whenever possible, only one type of inhaler should be prescribed. If a combination is unavoidable, combinations of DPIs are preferable to MDI and DPI. The Diskhaler seems to be the most foolproof device.